Results 81 to 90 of about 6,100,243 (291)
Fluctuations of Energy Loss in Semiconductor Detectors
IEEE Transactions on Nuclear Science, 1966 Significant fluctuations and broadening of the energy-loss spectrum are expected in certain cases of passage of charged particles through "thin" detectors. Experimental measurements of this phenomenon (by use of lithium-drifted silicon detectors) are in good agreement with the rigorous theory of Vavilov, as tabulated by Seltzer and Berger.
Maccabee, Howard D. +2 more
openaire +2 more sources
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
High Energy X-Ray Detection by MicroPattern Gaseous Detector
Frontiers in Biomedical TechnologiesPurpose: The paper aims to discuss the response of the Micro-Mesh Gaseous Structure (Micromegas) detector to high-energy X-ray with 2.3 MeV energy using photon to neutron converters in addition to optimization of the detector components by Monte Carlo ...
Saeedeh Khezripour +1 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Sensitivity of a low threshold directional detector to CNO-cycle solar neutrinos
European Physical Journal C: Particles and Fields, 2018 A first measurement of neutrinos from the CNO fusion cycle in the Sun would allow a resolution to the current solar metallicity problem. Detection of these low-energy neutrinos requires a low-threshold detector, while discrimination from radioactive ...
R. Bonventre, G. D. Orebi Gann
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
IEEE AccessEnergy detection is crucial during initial cell selection as it effectively assists the User Equipment (UE) in swiftly identifying a suitable Radio Frequency (RF) channel from numerous candidates.
Bitna Kim, Juyeop Kim
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source