Results 131 to 140 of about 1,363,403 (314)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Life cycle assessment of electric vehicles
, 2015 A life cycle analysis report commissioned by the Energy Efficiency and Conservation Authority (EECA) has found that electric vehicles (EVs) are better for the New Zealand environment than petrol or diesel powered vehicles, across the lifecycle of the ...
Energy Efficiency and Conservation Authority
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FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Effectiveness of energy efficiency certificates as drivers for industrial energy efficiency projects
, 2020 Policies for steering energy efficiency projects have multiple implications. Among others: economic opportunity, decrease of greenhouse gas emissions, security of supply, technological development. One of the key new instruments foreseen to support energy efficiency improvements is the energy efficiency certificate (EEC).
openaire +5 more sources
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
You have the power. 1997 Federal Energy Management Program report
, 1998 From 1985 to 1996, the Federal investment in energy efficiency totaled $2 billion. This investment achieved a cumulative savings of $6.3 billion in the nation`s energy bill when calculated from a 1985 baseline. The Energy Policy Act of 1992 and Executive
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
, 1995 SIGLEAvailable from British Library Document Supply Centre- DSC:4104.
Energy Efficiency Best Practice Programme (United Kingdom)
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ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source