Results 51 to 60 of about 3,628,620 (342)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Points of Consideration on Climate Adaptation of Solar Power Plants in Thailand: How Climate Change Affects Site Selection, Construction and Operation

Energies, 2021
Solar energy is planned to undergo large-scale deployment along with Thailand’s transformation to a carbon neutral society in 2050. In the course of energy transformation planning, the issue of energy infrastructure adaptation to climate change has often
Kampanart Silva, Pidpong Janta, Nuwong Chollacoop   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Efficiency of Energy Conversion in Thermoelectric Nanojunctions

, 2009
Using first-principles approaches, this study investigated the efficiency of energy conversion in nanojunctions, described by the thermoelectric figure of merit $ZT$. We obtained the qualitative and quantitative descriptions for the dependence of $ZT$ on
Baheti K., Beebe J. M., Chen Y. C., Chen Y. C., Chen Y. C., Cuevas J. C., Di Ventra M., Dubi Y., Finch C. M., Galperin M., Kaun C. C., Ke S. H., Kobayashi N., Lang N. D., Lang N. D., Liu Y. S., Ludoph B., Ma C. L., Malen J. A., Markussen T., Patton K. R., Paulsson M., Pauly F., Reddy P., Smit R. H. M., Tao N. J., Thygesen K. S., Wang B., Wang W., Wold D. J., Yang Z., Zhao J., Zheng X.   +32 more
core   +1 more source

H2-ARQ-relaying: spectrum and energy efficiency perspectives [PDF]

, 2011
In this paper, we propose novel Hybrid Automatic Repeat re-Quest (HARQ) strategies used in conjunction with hybrid relaying schemes, named as H2-ARQ-Relaying.
Hoshyar, Reza, Imran, Muhammad Ali, Qi, Yinan, Tafazolli, Rahim   +3 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

What Motivates Companies to Take the Decision to Decarbonise?

Energies
What motivates industrial companies to decarbonise? While climate policy has intensified, the specific factors driving corporate decisions remain underexplored.
Stefan M. Buettner, Werner König, Frederick Vierhub-Lorenz, Marina Gilles   +3 more
doaj   +1 more source

Application of Artificial Neural Networks for Virtual Energy Assessment

Energies, 2021
A Virtual energy assessment (VEA) refers to the assessment of the energy flow in a building without physical data collection. It has been occasionally conducted before the COVID-19 pandemic to residential and commercial buildings.
Amir Mortazavigazar, Nourehan Wahba, Paul Newsham, Maharti Triharta, Pufan Zheng, Tracy Chen, Behzad Rismanchi   +6 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source