Results 61 to 70 of about 848,604 (282)

Influence of EEDI (Energy Efficiency Design Index) on Ship–Engine–Propeller Matching

open access: yesJournal of Marine Science and Engineering, 2019
With the increasingly strict international GHG (greenhouse gas) emission regulations, higher requirements are placed on the propulsion system design of conventional ships. Playing an important role in ship design, construction and operation, ship–engine–propeller matching dominantly covers the CO2 emission of the entire ship.
Huilin Ren, Yu Ding, Congbiao Sui
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Analysis and evaluation of fuel cell technologies for sustainable ship power: Energy efficiency and environmental impact

open access: yesEnergy Conversion and Management: X
Amid growing emphasis on achieving carbon neutrality, this study conducts a thorough assessment of different fuel cell technologies for their suitability as primary ship power sources.
Zhe Wang   +5 more
doaj   +1 more source

POWER REDUCTION CONSIDERATIONS FOR BULK CARRIERS WITH RESPECT TO NOVEL ENERGY EFFICIENCY REGULATIONS

open access: yesBrodogradnja, 2022
After introducing an energy efficiency design index (EEDI) in 2011, International Maritime Organization (IMO) pursued their short- and long-term goals to reduce greenhouse gas (GHG) emissions from ships by presenting, among others, an energy efficiency ...
Milan Kalajdžić   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Research on Building Energy Efficiency Management and Index Evaluation System

open access: yesChemical Engineering Transactions, 2015
Building energy efficiency and index evaluation system was not only the important key to decide whether a building was energy saving or not but also method of the result of the evaluation system.
P.W. Xu   +4 more
doaj   +1 more source

Optimization of large homogeneous air Cherenkov arrays and application to the design of a 1TeV-100TeV gamma-ray observatory

open access: yes, 2009
At the time large air Cherenkov arrays are being discussed for future gamma-ray observatories, we review the relationship between the targeted capabilities and the main design parameters taking into account construction costs.
Acciari   +19 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Energy-Efficient Coordinated Multi-Cell Multigroup Multicast Beamforming with Antenna Selection

open access: yes, 2017
This paper studies energy-efficient coordinated beamforming in multi-cell multi-user multigroup multicast multiple-input single-output systems. We aim at maximizing the network energy efficiency by taking into account the fact that some of the radio ...
Chatzinotas, Symeon   +5 more
core   +1 more source

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