Results 111 to 120 of about 2,591,056 (296)

Classification criteria for coal bursting liability based on portable Leeb hardness testing

Meitan xuebao
Determining the bursting liability of coal is one of the main basis for evaluating the bursting risk degree of coal burst mine. Considering the complexity of existing classification procedures for determining coal bursting liability, a new method based ...
Yixin ZHAO, Zhe YANG, Ronghuan XIE, Tao WANG, Liangchen ZHAO   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Classification criteria for coal bursting liability based on scratch testing

Meitan kexue jishu
The bursting liability is an inherent property of coal-rock masses prone to impact failure, serving as an intrinsic factor for coal mines to induce rockburst accidents and a critical indicator for assessing the risk of rockburst. However, the traditional
Yixin ZHAO, Tao WANG, Zhe YANG, Ronghuan XIE   +3 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Damage characteristics and energy storage evolution law of coal with pressure relief borehole

Meitan kexue jishu
In the environment of deep strong mining-induced stress, phenomena such as borehole collapse, closure and compaction are prone to occur in large-diameter pressure relief boreholes in coal seams, and the pressure relief effect shows obvious time-effect ...
Yanchun YIN, Tongbin ZHAO, Aiwen WANG, Chuanru YAO, Fangrui LIU, Xuepeng GAO   +5 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Evolution Law of Stress Field and Pressure Relief Effect of Coal Seam After Drilling

Energy Science & Engineering
As an effective means of coal burst prevention, large‐diameter drilling pressure relief technology have been widely used in coal burst mines in China. Engineering practice shows that drilling pressure relief has obvious time‐effect.
Yanchun Yin, Chuanru Yao, Yueyong Han, Yue Qiu, Changqing Li, Yang Chen   +5 more
doaj   +1 more source

Acoustic Emission and Infrared Radiation Energy Evolution in the Failure of Phosphate Rock: Characteristics and Damage Modeling

Applied Sciences
Accurately characterizing the energy evolution during rock failure is crucial in understanding instability mechanisms and enabling the real-time monitoring and early warning of geological hazards in mining and geotechnical engineering.
Manqing Lin, Xuan Peng, Ye Chen, Qi Liao, Xianglong Lu, Xiqi Liu   +5 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source