Results 71 to 80 of about 2,591,056 (296)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The roof anchor cable in deep high stress roadway under the combined action of tension, shear, torsion and so on, could release accumulated strain energy instantaneously, causing the ejection accident due to anchor cable breaking, which seriously affects
Min TU +3 more
doaj +1 more source
Evolution of perturbations in distinct classes of canonical scalar field models of dark energy
Dark energy must cluster in order to be consistent with the equivalence principle. The background evolution can be effectively modelled by either a scalar field or by a barotropic fluid.The fluid model can be used to emulate perturbations in a scalar ...
B. Novosyadlyj +7 more
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Coquaternionic quantum dynamics for two-level systems [PDF]
The dynamical aspects of a spin- 1/2 particle in Hermitian coquaternionic quantum theory is investigated. It is shown that the time evolution exhibits three di erent characteristics, depending on the values of the parameters of the Hamiltonian.
Brody, DC, Graefe, EM
core +3 more sources
A model for the quasi-static growth of brittle fractures: existence and approximation results
We give a precise mathematical formulation of a variational model for the irreversible quasi-static evolution of brittle fractures proposed by G.A. Francfort and J.-J. Marigo, and based on Griffith's theory of crack growth. In the two-dimensional case we
Maso, Gianni Dal, Toader, Rodica
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
To investigate the effects of wet-dry cycling on the dynamic tensile strength and failure characteristics of limestone, this study conducted dynamic impact loading experiments on limestone specimens subjected to varying numbers of wet-dry cycles using a ...
Wusi Dai +6 more
doaj +1 more source

