Results 61 to 70 of about 3,509,597 (298)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Nucleon Flow and Fragment Flow in Heavy Ion Reactions

, 1993
The collective flow of nucleons and that of fragments in the 12C + 12C reaction below 150 MeV/nucleon are calculated with the antisymmetrized version of molecular dynamics combined with the statistical decay calculation.
A. Ono, A. Ono, A. Ono, A. Volkov, Akira Ono, F. Pühlhofer, F. Sébille, G. D. Westfall, H. Feldmeier, H. Horiuchi, Hisashi Horiuchi, J. Aichelin, J. Dechargé, J. Péter, T. Maruyama, Toshiki Maruyama   +15 more
core   +1 more source

Inertia effects in rheometrical flow systems Part 3: Some energy considerations with respect to the flow field in the balance rheometer [PDF]

, 1981
Following up a previous paper by one of the presents authors on the flow field in the balance rheometer, inertia effects being included, in this paper some energy considerations with respect to this flow field are presented.
Makh, S.S., Waterman, H.A.
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-objective optimization of ORC geothermal conversion system integrated with life cycle assessment

E3S Web of Conferences, 2018
This paper details the development of a systematic methodology to integrated life cycle assessment (LCA) with thermo-economic models and to thereby identify the optimal exploitation schemes of geothermal resources. Overall geothermal systems consist of a
Matuszewska Dominika, Kuta Marta, Górski Jan   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Highly magnetized region in pulsar wind nebulae and origin of the Crab gamma-ray flares

, 2012
The recently discovered gamma-ray flares from the Crab nebula are generally attributed to the magnetic energy release in a highly magnetized region within the nebula. I argue that such a region naturally arises in the polar region of the inner nebula. In
Abdo, Bednarek, Begelman, Begelman, Bogovalov, Bogovalov, Bogovalov, Buehler, Bykov, Cerutti, Clausen-Brown, Coroniti, de Jager, Del Zanna, Del Zanna, Guilbert, Kennel, Kirk, Kirk, Komissarov, Komissarov, Lyubarsky, Lyubarsky, Lyubarsky, Lyubarsky, Lyubarsky, Lyubarsky, Lyubarsky, Michel, Michel, Mizuno, Pétri, Rees, Sironi, Striani, Sturrock, Tavani, Uzdensky, Vittorini, Weisskopf, Y. E. Lyubarsky, Yuan, Zenitani   +42 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Elemental Mercury Removal over CeO₂/TiO₂ Catalyst Prepared by Sol–Gel Method

Applied Sciences, 2020
Elemental mercury (Hg0) emitted from a coal-fired boiler is a serious menace and challenge to humans. Using high-efficiency CeO2/TiO2 catalysts to enhance the conversion from elemental mercury to oxidized mercury is a promising approach to reducing Hg0 ...
Qiang Lv, Chang’an Wang, Yang He, Ming Cai, Defu Che   +4 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source