Results 81 to 90 of about 1,107,923 (314)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Multiscale modeling for multiphase flow and reactive mass transport in subsurface energy storage: A review [PDF]
Modeling of multiphase flow and reactive mass transport in porous media remains a pivotal challenge in the realm of subsurface energy storage, demanding a nuanced understanding across varying scales. This review paper presents a comprehensive overview of
Voskov, Denis +4 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Energies, 2019 One of the most important sources of air pollution, especially in urban areas, is the exhaust emissions from passenger cars. New European emissions regulations, to minimize the gap between manufacturer-reported emissions and those emitted on the road ...
Timothy Bodisco, Ali Zare
doaj +1 more source
Evaluation of Virtual Refrigerant Mass Flow Sensors
, 2012 Refrigerant mass flow rate is an important measurement for monitoring equipment performance and enabling fault detection and diagnostics. However, a traditional mass flow meter is expensive to purchase and install. A virtual refrigerant mass flow sensor (
Kim, Woohyun, Braun, James E.
core
, 1992 Trends in energy consumption and assessment of energy sources are discussed. Specific topics discussed include: energy flow charts; comparison of energy use with 1990 and earlier years; supply and demand of fossil fuels (oils, natural gas, coal ...
Borg, I. Y., Briggs, C. K.
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
An experimental comparison of min-cut/max- flow algorithms for energy minimization in vision
, 2004 Minimum cut/maximum flow algorithms on graphs have emerged as an increasingly useful tool for exactor approximate energy minimization in low-level vision.
Yuri Boykov +3 more
core
Anomalous Behavior of Anion Exchange Membrane during Operation of a Vanadium Redox Flow Battery
, 2019 Vanadium redox flow batteries (VRFBs) are becoming an integral component of renewable energy solutions, microgrids, and backup storage systems. The reduction in cell resistance due to advancements in the electrode and overall component design allows flow
Nyunt Wai +19 more
core +1 more source