Results 51 to 60 of about 409,571 (264)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Enhancing the efficiency of hybrid Schottky diode by decoration of 2D Cs:ZnO nanosheets with CNTs via a facile co-precipitation approach

Materials Research Express
The Cs:ZnO@CNTs nanocomposite was synthesized by chemical co-precipitation method and characterized using XRD, EDX, SEM, and TEM techniques, which revealed small crystalline size, high atomic density, and large surface area. The thin films showed intense
A Al-Sayed, Miad Ali Siddiq, Elsayed Elgazzar   +2 more
doaj   +1 more source

Structural and Optical Characterization of Porous NiV₂O₆ Films Synthesized by Nebulizer Spray Pyrolysis for Photodetector Applications

Micromachines
NiV2O6 thin films were grown on glass slides with varying thicknesses using nebulizer spray pyrolysis. The impact of thickness on the thin films’ optical, structural, morphological, and electrical characteristics was systematically investigated.
Ahmed Kotbi, Islam M. El Radaf, Ilham Hamdi Alaoui, Anna Cantaluppi, Andreas Zeinert, Abdelilah Lahmar   +5 more
doaj   +1 more source

Fotoluminescência em materiais com desordem estrutural Photoluminescence in disordered materials

Cerâmica, 2004
A grande maioria dos estudos fotoluminescentes foram realizados com materiais cristalinos, cuja emissão ocorre em temperaturas criogênicas, limitando a aplicação destes materiais. Por sua vez, determinados sólidos com alta densidade de defeitos (amorfos),
P. R. de Lucena, F. M. Pontes, C. D. Pinheiro, E. Longo, P. S. Pizani, S. Lázaro, A. G. Souza, I. M. G. dos Santos   +7 more
doaj   +1 more source

The energy spectrum and the electrical conductivity of graphene with substitution impurity

Condensed Matter Physics, 2020
The effect of substitution atoms on the energy spectrum and the electrical conductivity of graphene was investigated in a Lifshitz one-electron tight-binding model.
S.P. Repetsky, I.G. Vyshyvana, S.P. Kruchinin, R.M. Melnyk, A.P. Polishchuk   +4 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Integration of p-Type PdPc and n-Type SnZnO into Hybrid Nanofibers Using Simple Chemical Route for Enhancement of Schottky Diode Efficiency

Physics
Palladium phthalocyanine (PdPc) and palladium phthalocyanine integrated with tin–zinc oxide (PdPc:SnZnO) were prepared using a simple chemical approach, and their structural and morphological properties were identified using X-ray diffraction, energy ...
A. Al-Sayed, Miad Ali Siddiq, Elsayed Elgazzar   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source