Results 61 to 70 of about 490,774 (289)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

MEMS vibrational energy harvesters [PDF]

Science and Technology of Advanced Materials, 2019
In this paper, we look into the fundamental mechanism to retrieve the power from physical vibrations by using microelectromechanical systems (MEMS) energy harvesters. An analytical model is presented for the velocity-damped resonant generator (VDRG) that delivers electrical power through the power enhancement mechanism using the mechanical resonance of
Hiroshi Toshiyoshi, Suna Ju, Hiroaki Honma, Chang-Hyeon Ji, Hiroyuki Fujita   +4 more
openaire   +3 more sources

Piezoelectric vibration energy harvester: Operating mode, excitation type and dynamics

Advances in Mechanical Engineering, 2022
Nowadays, with the rapid development of the intelligent era and the concept of Internet of Things being proposed, more and more sensors will play a more important role.
Weipeng Zhou, Dongmei Du, Qian Cui, Ziming Yang, Chang Lu, Yuhao Wang, Qing He   +6 more
doaj   +1 more source

Energy Recovery and Energy Harvesting in Electric and Fuel Cell Vehicles, a Review of Recent Advances

IEEE Access, 2023
This review article examines the crucial role of energy harvesting and energy recovery in the design of battery electric vehicles (BEVs) and fuel cell hybrid electric vehicles (FCHEVs) as these vehicles have limited onboard power sources.
Seyed Mohammad Hosseini, Mehdi Soleymani, Sousso Kelouwani, Ali Akrem Amamou   +3 more
doaj   +1 more source

Energy harvesting: a review of the interplay between structure and mechanism [PDF]

, 2008
The science of energy harvesting has recently undergone radical change, with the advent of new materials exploiting mechanisms fundamentally different from those of traditional solar cells.
Andrews, David L
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Nanomaterials for Energy Harvesting

Nanomaterials, 2023
Energy harvesting is no longer simply an academic issue; it has grown into a problem with real industrial and even social significance [...]
openaire   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

High-performance, mini modules (∼1 cm2) of halide perovskite indoor photovoltaics with carbon counter electrode and sensor powering

JPhys Energy
Halide perovskite indoor photovoltaics present a promising pathway for sustainably powering the rapidly growing network of wireless sensors in the Internet of Things.
Hugo Decitre, Adele McDaid, Sean Doughlas, Benedikta Bokedal, Sahil Verma, Rajasekhar Muddam, Tasmiat Rahman, Lethy Krishnan Jagadamma   +7 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source