Results 61 to 70 of about 156,519 (267)

Investigation of seasonal soil moisture and temperature variations underneath a waffle raft foundation built on reactive soil

Scientific Reports
Lightweight structures, such as residential foundations, built on reactive soils experience stability issues due to the soil’s high shrink-swell movements.
S. Mediliye Gedara, P. L.P. Wasantha, B. Teodosio, E. Yaghoubi, R. van Staden, M. Guerrieri   +5 more
doaj   +1 more source

Challenges for the Ukrainian energy industry

Security and Defence Quarterly, 2014
<i>Reform of the energy sector is very important, both for the Ukrainian economy and for the reputation of Ukraine in Europe. Since independence, the energy sector, and especially the gas sector, has been totally in transparency and a major area of corruption.
openaire   +2 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Fire in a High-Rise Building: Study of the Behaviour of Burnt Gases in a Ventilated and Unventilated Upper Compartment

Journal of Combustion
This paper presents a comparative study between natural and mechanical smoke extraction during fire in a high-rise building. Experiments were conducted in a small scale F + 1 building with dimensions 1.23 × 1.23 × 2.0 m. A stair-well of dimensions 0.22 × 
Rodrigue Bela Ndjie, El-Kebir Ahmed, Philippe Onguene Mvogo, Justin Tégawendé Zaida, Ruben Mouangue   +4 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Energy Efficiency in Industrial Utilities

, 2011
The demand for electrical energy has increased tremendously over the last 25 years; its importance is such that it is now a vital component of any nation’s economic progress. Increase in population has increased the energy requirements, coupled with the industrialization & socio-economic responsibilities; the energy supply has not kept pace with the ...
Kini, P. Giridhar, Bansal, Ramesh C.
openaire   +3 more sources