Results 61 to 70 of about 208,435 (291)

Effect of Swirl Inflow on Flow Pattern and Pressure Fluctuation onto a Single-Elbow Pipe in Japan Sodium-Cooled Fast Reactor

Journal of Fluid Science and Technology, 2012
As part of the development of a flow-induced vibration evaluation methodology for the primary cooling piping in Japan sodium-cooled fast reactor, important factors were discussed in evaluating the flow-induced vibration for the hot-leg piping.
Hidemasa YAMANO, Hiromi SAGO, Kazuo HIROTA, Satoshi HAYAKAWA, Yang XU, Masaaki TANAKA, Takaaki SAKAI   +6 more
doaj   +1 more source

Future Applications of Biotechnology to the Energy Industry [PDF]

Frontiers in Microbiology, 2016
There has been a dramatic growth in the production of biofuels in recent times. Global biofuel production tripled between 2000 and 2007, and biofuels accounted for about 1.6% of global transportation fuel in 2012 (International Energy Agency). At the time of this writing, 2015, ethanol production is by far the greatest contribution by biotechnology to ...
John Joseph Kilbane, John Joseph Kilbane
openaire   +3 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Development of a Methodology for Obtaining Solid Models of Products That Are Objects of Reverse Engineering Using the Example of the Capstone Micro-GTU C 65

Modelling
Currently, about a thousand micro gas turbine units of small and medium capacity are in operation in the Russian Federation, which are used as an autonomous power source at critical infrastructure facilities.
Sergey Osipov, Ivan Komarov, Olga Zlyvko, Andrey Vegera, George Gertsovsky   +4 more
doaj   +1 more source

Experimental Investigation on Transient Pressure Characteristics in a Helico-Axial Multiphase Pump

Energies, 2019
In oil and gas exploitation, the multiphase pump is a vital piece of equipment to guarantee production with high efficiency and stable operation. The complicated pattern of multiphase flow in the multiphase pump affects the pump performance; for this ...
Yun Xu, Shuliang Cao, Takeshi Sano, Tokiya Wakai, Martino Reclari   +4 more
doaj   +1 more source

Energy Management in Energy-Intensive Industries: Developing a Conceptual Map [PDF]

Brazilian Archives of Biology and Technology, 2019
This paper presents the development of a conceptual map regarding energy management applied to industry. The energy issue is currently of great relevance, especially for the so-called energy-intensive industries related to high energy consumption and ...
Vilson Roiz Gonçalves Rabelo da Silva, Eduardo de Freitas Rocha Loures, Edson Pinheiro de Lima, Sergio Eduardo Gouvêa da Costa   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Energy in the Americas; Energy in the Americas [PDF]

, 2021
Understanding the history of energy and the evolving place of energy in society is essential to facing the changing future of energy production. Across North and South America, national and localized understandings of energy as a common, public, or ...

core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Investigation of seasonal soil moisture and temperature variations underneath a waffle raft foundation built on reactive soil

Scientific Reports
Lightweight structures, such as residential foundations, built on reactive soils experience stability issues due to the soil’s high shrink-swell movements.
S. Mediliye Gedara, P. L.P. Wasantha, B. Teodosio, E. Yaghoubi, R. van Staden, M. Guerrieri   +5 more
doaj   +1 more source