Porous materials in building energy technologies—a review of the applications, modelling and experiments [PDF]
, 2018 Improving energy efficiency in buildings is central to achieving the goals set by Paris agreement in 2015, as it reduces the energy consumption and consequently the emission of greenhouse gases without jeopardising human comfort.
Esfahani, Javad Abolfazli +2 more
core +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
On Binding Energy of Trions in Bulk Materials
, 2018 We study the negatively $T^{-}$ and positively $T^{+}$ charged trions in bulk materials in the effective mass approximation within the framework of a potential model.
Filikhin, Igor +2 more
core +1 more source
Designing interfaces in energy materials applications with first-principles calculations
npj Computational Materials, 2019 Materials for energy-related applications, which are crucial for a sustainable energy economy, rely on combining materials that form complex heterogenous interfaces.
K. Butler +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Evaluation of Optical and Acoustical Properties of Ba1−xSrxTiO3 Thin Film Material Library via Conjugation of Picosecond Laser Ultrasonics with X-ray Diffraction, Energy Dispersive Spectroscopy, Electron Probe Micro Analysis, Scanning Electron and Atomic Force Microscopies [PDF]
, 2021 Sathyan Sandeep +7 more
openalex +1 more source
Energy scaling law for nanostructured materials [PDF]
, 2017 The equilibrium binding energy is an important factor in the design of materials and devices. However, it presents great computational challenges for materials built up from nanostructures.
Hyldgaard, Per +6 more
core +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source