Results 101 to 110 of about 18,261,083 (260)

Study of nanoemulsions using carvacrol/MCT-(Oleic acid-potassium oleate)/ Tween 80 ®- water system by low energy method. [PDF]

Heliyon, 2023
Santamaría E, Maestro A, Vilchez S, González C.   +3 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Analysis and Reduction of Cogging Torque of Permanent Magnet Synchronous Wind Generators Based on the Magnetic Field Modulation Mechanism

CES Transactions on Electrical Machines and Systems
In this paper, a magnetic field modulation model considering the influence of phase angles is established for the analysis and weakening of the cogging torque of the permanent magnet synchronous wind generations.
Zexing Li, Chao Liu, Yiwen Fan, Zixuan Zhang, Jiakuan Xia   +4 more
doaj   +1 more source

Calculation of horizontal displacement of loess fill slope supported by frame prestressed anchors based on minimum potential energy method. [PDF]

Sci Rep, 2022
Zhao Z, Zhu Y, Ye S.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Regional Super ESPC Saves Energy and Dollars at NASA's Johnson Space Center

, 2001
This case study about energy saving performance contacts (ESPCs) presents an overview of how the NASA's Johnson Space Flight Center established an ESPC contract and the benefits derived from it.
Program, Federal Energy Management
core  

A highly accurate metadynamics-based Dissociation Free Energy method to calculate protein-protein and protein-ligand binding potencies. [PDF]

Sci Rep, 2022
Wang J, Ishchenko A, Zhang W, Razavi A, Langley D.   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Energy-Efficient Wireless Sensor Network with an Unequal Clustering Protocol Based on a Balanced Energy Method (EEUCB). [PDF]

Sensors (Basel), 2021
Jasim AA, Idris MYI, Razalli Bin Azzuhri S, Issa NR, Rahman MT, Khyasudeen MFB.   +5 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source