Results 81 to 90 of about 44,657,267 (321)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

On a nonolinear wave equation in unbounded domains

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1988
We study existence and uniqeness of the nonlinear wave equation∂2u∂t2+M(x,∫|∇u(x,t)|2dx+∫|u(x,t)|2dx)(−Δu+u)=0in unbounded domains. The above model describes nonlinear wave phenomenon in non-homogeneous media.
Carlos Frederico Vasconcellos
doaj   +1 more source

Buckling Analysis for Wind Turbine Tower Design: Thrust Load versus Compression Load Based on Energy Method

open access: yesEnergies, 2020
Tubular steel towers are the most common design solution for supporting medium-to-high-rise wind turbines. Notwithstanding, historical failure incidence records reveal buckling modes as a common type of failure of shell structures.
Yang Ma   +2 more
doaj   +1 more source

Energy Spectrum Extraction and Optimal Imaging via Dual-Energy Material Decomposition

open access: yes, 2015
Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition.
Niu, Tianye   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Diagnosis of axial displacement in transformer windings using finite element analysis

open access: yesJournal of Mathematical Sciences and Modelling, 2018
Transformer is one of the main equipment in the power system and power quality of the power system mainly depends on the working of the power transformer. Leakage reactance is one of the main parameters of the transformer.
Kamran Dawood   +2 more
doaj   +1 more source

A block diagonalization theorem in the energy-momentum method [PDF]

open access: yes, 1989
We prove a geometric generalization of a block diagonalization theorem first found by the authors for rotating elastic rods. The result here is given in the general context of simple mechanical systems with a symmetry group acting by isometries on a ...
Lewis, D.   +3 more
core  

Simulations of energetic beam deposition: from picoseconds to seconds

open access: yes, 1998
We present a new method for simulating crystal growth by energetic beam deposition. The method combines a Kinetic Monte-Carlo simulation for the thermal surface diffusion with a small scale molecular dynamics simulation of every single deposition event ...
A. E. DePristo   +48 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Self-similar solutions with compactly supported profile of some nonlinear Schrodinger equations

open access: yesElectronic Journal of Differential Equations, 2014
``Sharp localized'' solutions (i.e. with compact support for each given time t) of a singular nonlinear type Schr\"odinger equation in the whole space $\mathbb{R}^N$ are constructed here under the assumption that they have a self-similar structure. It
Pascal Begout, Jesus Ildefonso Diaz
doaj  

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