Results 121 to 130 of about 2,110,233 (290)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
The fluctuation analysis of public opinion energy: Modeling social group opinion base on the event of social networks. [PDF]
Intell Syst Appl, 2022 Shi Y, Qi J, Wang R.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A study on heat transfer load in large space buildings with stratified air-conditioning systems based on building energy modeling: Model validation and load analysis. [PDF]
Sci Prog, 2021 Zhang Y, Lu J, Jiang X, Shen S, Wang X.
europepmc +1 more source
Representation of the Short-Range Interactions in Liquid Helium via Modified Hard Sphere Potentials
, 2001 In this paper we propose five different modifications of the hard sphere potential for the modeling a short-range repulsion and the calculation of thermodynamic and transport properties of liquid He4.
Rovenchak, A. A., Vakarchuk, I. O.
core
Energy models and energy policy problems [PDF]
, 2005 I have been involved in energy modelling for planning and policy making for more than ten years now and I am still convinced that systematic and careful modelling can contribute to better decisions in the energy policy area. I think I should make this statement right at the beginning, because my contribution will be somewhat critical.
openaire +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source