Results 81 to 90 of about 7,343,696 (302)

Embedded ONNX Versus Python Sidecar Inference for Anomaly-Aware Availability Response in Spring Boot Microservices: An Architectural Evaluation

Journal of Cybersecurity and Privacy
Availability-oriented monitoring may require low-latency anomaly inference, but deploying a lightweight model as a separate service adds process, serialization, and network-path overhead.
Tymofii Bondaruk, Oleksandr Tsypliak, Vadym Shkarupylo, Volodymyr Artemchuk   +3 more
doaj   +1 more source

Techno-economic data for a multi-model approach to decarbonisation of the Irish private car sector

Data in Brief, 2017
These data and analyses support the research article “From technology pathways to policy roadmaps to enabling measures – A multi-model approach” Mulholland et al. (2017) [1].
Eamonn Mulholland, Fionn Rogan, Brian P.Ó Gallachóir   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Modelling OECD Industrial Energy Demand: Asymmetric Price Responses and Energy – Saving Technical Change [PDF]

The industrial sector embodies a multifaceted production process consequently modelling the ‘derived demand’ for energy is a complex issue; made all the more difficult by the need to capture the effect of technical progress of the capital stock.
Olutomi I Adeyemi, Lester C. Hunt
core  

Introduction to Energy Systems Modelling

, 2018
Introduction to Energy Systems modelling Content: Context What do we mean by energy system? What is energy system modelling?
Beltramo, Agnese (6002534), Taliotis, Constantinos, Gardumi, Francesco, Rogner, Holger, Shivakumar, Abhishek, Beltramo, Agnese, Howells, Mark (6002540), Ramos, Eunice (6002531), Shivakumar, Abhishek (6002525), Howells, Mark, Rogner, Holger (6002537), Taliotis, Constantinos (6002519), Sridharan, Vignesh (6002528), Sridharan, Vignesh, Ramos, Eunice, Gardumi, Francesco (6002522)   +15 more
core   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Analyzing the effects of uncertainties on the modelling of low-carbon energy system pathways

, 2020
Decarbonization is an important goal of the future energy transition, but its modelling is also subject to several uncertainties. Here we investigate the impacts of such uncertainties through analyzing the overall performance and operation of a modelled ...
Pilpola, Sannamari, Lund, Peter
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source