Results 121 to 130 of about 252,020 (311)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Energy of graphs and digraphs [PDF]

open access: yes, 2010
vii, 80 leaves ; 29 cmThe energy of a graph is the sum of the absolute values of the eigenvalues of its adjacency matrix. The concept is related to the energy of a class of molecules in chemistry and was first brought to mathematics by Gutman in 1978 (
University of Lethbridge. Faculty of Arts and Science   +1 more
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Beyond graph energy: Norms of graphs and matrices

open access: yesLinear Algebra and its Applications, 2016
54 pages.
openaire   +3 more sources

Energy Information Outline, 2010

open access: yes, 2010
A historical view and distribution of energy in ...

core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Strongly Regular Graphs with Maximal Energy

open access: yes
The energy of a graph is the sum of the absolute values of the eigenvalues of its adjacency matrix. Koolen and Moulton have proved that the energy of a graph on n vertices is at most n(1 + √n)/2, and that equality holds if and only if the graph is ...
Haemers, W.H.
core  

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

GRAPH ENERGY OF THE COPRIME GRAPH ON GENERALIZED QUATERNION GROUP

open access: yesBarekeng
This paper investigates the Degree Square Sum Energy , Degree Exponent Energy , and Degree Exponent Sum Energy  of the coprime graph on generalized quaternion group ​.
Miftahurrahman Miftahurrahman   +3 more
doaj   +1 more source

On the Adjacency, Laplacian, and Signless Laplacian Spectrum of Coalescence of Complete Graphs

open access: yesJournal of Mathematics, 2016
Coalescence as one of the operations on a pair of graphs is significant due to its simple form of chromatic polynomial. The adjacency matrix, Laplacian matrix, and signless Laplacian matrix are common matrices usually considered for discussion under ...
S. R. Jog, Raju Kotambari
doaj   +1 more source

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