Results 51 to 60 of about 252,020 (311)
NeMeSys – Energy Adaptive Graph Pattern Matching on NUMA-based Multiprocessor Systems
, 2019 NeMeSys is a NUMA-aware graph pattern processing engine, which leverages intelligent resource management for energy adaptive processing. With modern server systems incorporating an increasing amount of main memory, we can store graphs and compute ...
Ungethüm, Annett +4 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The energy of graphs and matrices
Journal of Mathematical Analysis and Applications, 2007 We extend the concept of graph energy, introduced by Gutman, to matrices. We give upper and lower bounds on matrix energy extending previous results for graphs. In particular, we estimate the energy of almost all graphs.
openaire +2 more sources
Bond Graph Based Stability Analysis of a Railway Traction System [PDF]
, 2005 This paper emphasises the interest of the Bond Graph approach for analysis and system design of heterogeneous and multi-field devices. In particular, the local stability analysis of non linear systems can be directly derived from the linearised Causal ...
Sareni, Bruno +3 more
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Graph theory-based approach for energy corridors network to Greece
, 2011 PurposeThe European Union (EU) energy supply environment is changing significantly and in a dynamic way, establishing the issue of safe energy imports as main priority. Greece relies heavily on energy imports. Furthermore, Greece aims to be elevated into
Flouri, M +9 more
core +1 more source
A template-based design methodology for graph-parallel hardware accelerators [PDF]
, 2017 Graph applications have been gaining importance in the last decade due to emerging big data analytics problems such as Web graphs, social networks, and biological networks.
Burns, S. +5 more
core +1 more source