Results 111 to 120 of about 11,163,126 (353)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Study on optimization and mechanism of CO2 injection to enhance oil recovery in mid-deep heavy oil reservoirs

open access: yesFrontiers in Energy Research
In order to improve the oil recovery of mid-deep heavy oil reservoirs, this study investigates the efficiency of enhanced oil recovery and the mechanisms of oil displacement in mid-deep heavy oil reservoirs using different injected gases (N2, CH4, CO2 ...
Xiaokun Zhang   +6 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Disposition Choices Based on Energy Footprints instead of Recovery Quota [PDF]

open access: yes
This paper addresses the impact of disposition choices on the energy use of closed-loop supply chains. In a life cycle perspective, energy used in the forward chain which is locked up in the product is recaptured in recovery.
Krikke, H.R., Zuidwijk, R.
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

A return to normality: A descriptive qualitative interview study exploring the patient experience of gout flare resolution

open access: yesArthritis Care &Research, Accepted Article.
Objectives While the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semi‐structured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

Feasibility study of fracturing flowback fluid degradation by dielectric barrier discharge plasma

open access: yesScientific Reports
Fracturing flowback fluid, which is the waste fluid generated following the hydraulic fracturing of oil wells, has garnered significant attention in recent years regarding its safe treatment technologies. Low-temperature plasma water treatment technology
Meiqi Shi   +4 more
doaj   +1 more source

Research on the Development Mechanism of Air Thermal Miscible Flooding in the High Water Cut Stage of Medium to High Permeability Light Oil Reservoirs

open access: yesEnergies
Currently, the development of oil reservoirs with high water cut faces numerous challenges, including poor economic efficiency, difficulties in residual oil recovery, and a lack of effective development technologies.
Daode Hua   +8 more
doaj   +1 more source

Analysis of the Energy Efficiency of a Pneumatic Booster Regulator with Energy Recovery

open access: yesApplied Sciences, 2017
Pneumatic booster regulators (PBR) are in great demand in modern pneumatic systems for their energy-saving abilities. A new booster regulator with energy recovery (VBA-R) was proposed, and its energy efficiency was investigated by introducing the concept
Fan Yang   +3 more
doaj   +1 more source

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