Results 41 to 50 of about 462,910 (305)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sustainable CO2 adsorbents prepared by coating chitosan onto mesoporous silicas for large-scale carbon capture technology [PDF]

open access: yes, 2015
In this article, we report a new sustainable synthesis procedure for manufacturing chitosan/silica CO2 adsorbents. Chitosan is a naturally abundant material and contains amine functionality, which is essential for selective CO2 adsorptions.
Ganin, Alexey Y.   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

UHE tau neutrino flux regeneration while skimming the Earth

open access: yes, 2008
The detection of Earth-skimming tau neutrinos has turned into a very promising strategy for the observation of ultra-high energy cosmic neutrinos. The sensitivity of this channel crucially depends on the parameters of the propagation of the tau neutrinos
A. Letessier-Selvon   +6 more
core   +3 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Metabolic Regulation of Cardiac Regeneration

open access: yesFrontiers in Cardiovascular Medicine, 2022
The mortality due to heart diseases remains highest in the world every year, with ischemic cardiomyopathy being the prime cause. The irreversible loss of cardiomyocytes following myocardial injury leads to compromised contractility of the remaining ...
Xuewen Duan   +2 more
doaj   +1 more source

KL-KS Regeneration at High Energies [PDF]

open access: yes, 1970
The phenomenon of regeneration consists of a transformation of an incident long-lived neutral KL wave into a linear superposition of short- and long-lived states, KS and KL. It is expected to occur for any process in which K0 and \(\overline{{{K}_{0}}}\) interact differently.
H. Foeth   +10 more
openaire   +1 more source

Dark matter cores in the Fornax and Sculptor dwarf galaxies: joining halo assembly and detailed star formation histories [PDF]

open access: yes, 2014
We combine the detailed Star Formation Histories of the Fornax and Sculptor dwarf Spheroidals with the Mass Assembly History of their dark matter (DM) halo progenitors to estimate if the energy deposited by Supernova type II (SNeII) is sufficient to ...
Amorisco, Nicola C.   +2 more
core   +2 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Microfluidic devices as model platforms of CNS injury-ischemia to study axonal regeneration by regulating mitochondrial transport and bioenergetic metabolism

open access: yesCell Regeneration, 2022
Central nervous system (CNS) neurons typically fail to regenerate their axons after injury leading to neurological impairment. Axonal regeneration is a highly energy-demanding cellular program that requires local mitochondria to supply most energy within
Ning Huang, Zu-Hang Sheng
doaj   +1 more source

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