Results 51 to 60 of about 1,345,772 (312)

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Roundness and positioning deviation prediction in single point incremental forming using deep learning approaches

open access: yesAdvances in Mechanical Engineering, 2019
This article proposes a deep learning technique for the prevision of the geometric accuracy in single point incremental forming. Moreover, predicting geometric accuracy is one of the most crucial measures of part quality.
Sofien Akrichi   +3 more
doaj   +1 more source

Target magnetic moment orientation estimation method based on full magnetic gradient orthonormal basis function

open access: yesAIP Advances, 2022
Magnetic anomaly detection (MAD) is an effective method to detect the existence and localization of magnetic targets. Magnetic signal processing technology can extract target signals from complex background noise.
Yijie Qin   +5 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

An Island Grouping Genetic Algorithm for Fuzzy Partitioning Problems

open access: yesThe Scientific World Journal, 2014
This paper presents a novel fuzzy clustering technique based on grouping genetic algorithms (GGAs), which are a class of evolutionary algorithms especially modified to tackle grouping problems. Our approach hinges on a GGA devised for fuzzy clustering by
S. Salcedo-Sanz, J. Del Ser, Z. W. Geem
doaj   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

FPGA Realization of the Observer-Based Sliding Discrete Fourier Transform

open access: yesIEEE Access, 2022
Discrete Fourier transform (DFT) is a widely used method of signal analysis in digital signal processing. The DFT converts a signal from time domain to frequency domain for further processing.
Peter Plesznik   +2 more
doaj   +1 more source

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

A new hybrid method to estimate the single-diode model parameters of solar photovoltaic panel

open access: yesEnergy Conversion and Management: X, 2022
Today, photovoltaic (PV) panels represent a large part of total power generation. Photovoltaic cells and modules parameter estimation is a relevant field of research that plays a critical role in PV system modeling and simulation.
Souad Lidaighbi   +5 more
doaj  

Non-Linear Dynamics Analysis of Protein Sequences. Application to CYP450

open access: yesEntropy, 2019
The nature of changes involved in crossed-sequence scale and inner-sequence scale is very challenging in protein biology. This study is a new attempt to assess with a phenomenological approach the non-stationary and nonlinear fluctuation of changes ...
Xavier F. Cadet   +3 more
doaj   +1 more source

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