Results 71 to 80 of about 358,635 (311)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

An Island Grouping Genetic Algorithm for Fuzzy Partitioning Problems

The Scientific World Journal, 2014
This paper presents a novel fuzzy clustering technique based on grouping genetic algorithms (GGAs), which are a class of evolutionary algorithms especially modified to tackle grouping problems. Our approach hinges on a GGA devised for fuzzy clustering by
S. Salcedo-Sanz, J. Del Ser, Z. W. Geem
doaj   +1 more source

Target magnetic moment orientation estimation method based on full magnetic gradient orthonormal basis function

AIP Advances, 2022
Magnetic anomaly detection (MAD) is an effective method to detect the existence and localization of magnetic targets. Magnetic signal processing technology can extract target signals from complex background noise.
Yijie Qin, Maobin Li, Keyan Li, Yang Pan, Xiaofei Yang, Jun Ouyang   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

MSGM-Net: multi-scale general-modal network for disease and organ segmentation

Complex & Intelligent Systems
General and effective medical image segmentation methods achieve pixel-level accurate segmentation of lesions or organs. Existing 2-D networks have demonstrated their effectiveness on single-modal segmentation tasks, but difficult to exploit ...
Dayu Tan, Xiaoping Zhou, Chao Jiang, Xin Peng, Yansen Su, Weimin Zhong   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Non-Linear Dynamics Analysis of Protein Sequences. Application to CYP450

Entropy, 2019
The nature of changes involved in crossed-sequence scale and inner-sequence scale is very challenging in protein biology. This study is a new attempt to assess with a phenomenological approach the non-stationary and nonlinear fluctuation of changes ...
Xavier F. Cadet, Reda Dehak, Sang Peter Chin, Miloud Bessafi   +3 more
doaj   +1 more source

Transmission policies in wireless powered communication networks with energy cooperation

, 2016
Energy Harvesting (EH) has been recognized as one of the most appealing solutions for extending the devices lifetime in wireless sensor networks. Despite the vast literature available about ambient EH, in the last few years Energy Transfer (ET) has been ...
Biason, Alessandro, Zorzi, Michele, Alessandro Biason, Michele Zorzi   +3 more
core   +1 more source

Energy-Conscious Turbo Decoder Design: A Joint Signal Processing and Transmit Energy Reduction Approach [PDF]

IEEE Transactions on Vehicular Technology, 2013
Turbo codes (TCs) have been proposed to reduce the required transmission energy in wireless sensor networks (WSNs), although this gain must be offset by the turbo decoder's processing energy consumption (EC). Previously, it has not been possible to estimate this processing EC until a relatively late stage in the TC design process.
Liang Li 0013, Robert G. Maunder, Bashir M. Al-Hashimi, Mark Zwolinski, Lajos Hanzo   +4 more
openaire   +2 more sources