Results 41 to 50 of about 977,942 (315)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Turkey's renewable energy sources: Part 1. Historical development
The historical development of renewable energy sources of Turkey during 1853-2004 period is discussed. The renewable energy resources, which are investigated include energy, geothermal energy, biomass, wind energy and solar energy.
Ozgener O., Hepbasli A.
core +1 more source
Mixed-halide perovskite solar cells with the composition Cs0.1(MA0.17FA0.83)0.9Pb(I0.83Br0.17)3 were fabricated obtaining solar cells as glass/ITO/SnO2/triple-cation perovskite/HTL/Au, and subsequently used as photoanodes for efficient solar-driven water
Vera La Ferrara +8 more
doaj +1 more source
The multi-terminal voltage sourced converter medium-voltage DC (VSC-MVDC) distribution network has high prospects for future development, hence the proposed alternative for the AC distribution in commercial and industrial applications.
Patrobers Simiyu +6 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Electrical Power Production Facilities From Green Energy Sources
Green power refers to electricity supplied from more readily renewable energy sources than traditional electrical power sources. Green power products have become widespread in many electricity markets worldwide and can be derived from renewable energy ...
Demirbaş, Ayhan
core +1 more source
An analytical model for transient stability assessment of hybrid AC–DC transmission systems is formulated, implemented, and validated. The equal‐area criterion, as known from the transient stability analysis of AC power systems, is redeveloped for AC–DC ...
Peng Wang, Maren Kuschke, Kai Strunz
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

