Results 51 to 60 of about 2,118,124 (289)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Fault diagnosis technology overview for lithium‐ion battery energy storage station

open access: yesIET Energy Systems Integration
With an increasing number of lithium‐ion battery (LIB) energy storage station being built globally, safety accidents occur frequently. Diagnosing faults accurately and quickly can effectively avoid safe accidents.
Bin Li   +9 more
doaj   +1 more source

Ground-source heat pumps and underground thermal energy storage: energy for the future [PDF]

open access: yes, 2008
We need energy for space heating—but in most cases not where or when energy sources are available. Energy storage, which helps match energy supply and demand, has been practised for centuries, also in Norway.
Banks, D.   +4 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

True Performance Metrics in Electrochemical Energy Storage [PDF]

open access: yes, 2011
A dramatic expansion of research in the area of electrochemical energy storage (EES) during the past decade has been driven by the demand for EES in handheld electronic devices, transportation, and storage of renewable energy for the power grid (1–3 ...
Gogotsi, Yury, Simon, Patrice
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Hydrogen Energy Storage

open access: yes, 2019
The dominating trend of variable renewable energy sources (RES) continues to underpin the early retirement of baseload power generating sources such as coal, nuclear, and natural gas steam generators; however, the need to maintain system reliability remains the challenge.
openaire   +4 more sources

Opportunities for large-scale energy storage in geological formations in mainland Portugal [PDF]

open access: yes, 2018
This article presents the methodology and results of the first screening conducted in Portugal to identify geological formations suitable for large-scale storage of energy from renewable sources.
Carneiro, Júlio   +2 more
core   +1 more source

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