Results 51 to 60 of about 717,394 (302)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Fast Reaction Kinetics via Interfacial Mediation in Quasi- and All-Solid-State Lithium-Sulfur Batteries

Research
In recent years, lithium-sulfur batteries have attracted much interest owing to the natural abundance of sulfur and its high theoretical specific capacity (qth ≈ 1,672 mAh g−1), offering the potential to achieve cell-level energy densities exceeding 400 ...
Ke Wang, Yanjiao Ma, Torsten Brezesinski, Yuan Ma, Yuping Wu   +4 more
doaj   +1 more source

Ionomer-free and recyclable porous-transport electrode for high-performing proton-exchange-membrane water electrolysis

Nature Communications, 2023
Clean hydrogen production requires large-scale deployment of water-electrolysis technologies, particularly proton-exchange-membrane water electrolyzers (PEMWEs).
Jason K. Lee, Grace Anderson, Andrew W. Tricker, Finn Babbe, Arya Madan, David A. Cullen, José’ D. Arregui-Mena, Nemanja Danilovic, Rangachary Mukundan, Adam Z. Weber, Xiong Peng   +10 more
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

Enhancing Lithium‐Metal Battery Safety and Performance with Ether‐Aided Ionic Liquid Electrolytes

Advanced Energy & Sustainability Research
Electrolytes based on ionic liquids (ILs) are promising alternatives to conventional electrolyte systems due to their appealing properties, including enhanced safety owing to their high thermal stability and nonflammability, as well as their superior ...
Ziyuan Lyu, Dominik Stępień, Thomas Diemant, Alessandro Mariani, Dominic Bresser, Stefano Passerini   +5 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Fault diagnosis technology overview for lithium‐ion battery energy storage station

IET Energy Systems Integration
With an increasing number of lithium‐ion battery (LIB) energy storage station being built globally, safety accidents occur frequently. Diagnosing faults accurately and quickly can effectively avoid safe accidents.
Bin Li, Peiyu Chen, Guanzheng Li, Chao Li, Kaidi Zeng, Bin Liu, Xuebin Li, Qidi Huo, Kui Jiao, Chengshan Wang   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

μ 2T(n): a method for extracting the density dependent mobility in two-terminal nanodevices

Communications Engineering
Measuring carrier mobility as a function of the carrier density in semiconductors using the Hall effect is the gold standard for quantifying scattering mechanisms. However, for nanostructures, the standard Hall geometry is not applicable, and the density
Christian E. N. Petersen, Damon J. Carrad, Thierry Désiré, Daria Beznasyuk, Jung-Hyun Kang, Dāgs Olšteins, Gunjan Nagda, Dennis V. Christensen, Thomas Sand Jespersen   +8 more
doaj   +1 more source