Results 31 to 40 of about 243,884 (264)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ultralow Electrical Hysteresis along with High Energy‐Storage Density in Lead‐Based Antiferroelectric Ceramics

Advanced Electronic Materials, 2020
Antiferroelectric ceramics with extraordinary energy‐storage density have gained exponentially soaring attention for their applications in pulsed power capacitors. Nevertheless, high energy dissipation is a deficiency of antiferroelectric materials.
Kaiwei Huang, Guanglong Ge, Fei Yan, Bo Shen, Jiwei Zhai   +4 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Saturation effect on storage-dissipation properties and failure characteristics of red sandstone: Energy mechanism of water in preventing rockburst

International Journal of Coal Science & Technology
To investigate the effect of saturation on the storage-dissipation properties and failure characteristics of red sandstone, as well as the energy mechanism of rockburst prevention by water, a series of uniaxial compression and uniaxial loading–unloading ...
Yong Luo, Jiancheng Huang, Wuxing Wu, Xuefeng Si, Chuanqi Zhu   +4 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Recent advance of metal borohydrides for hydrogen storage

Frontiers in Chemistry, 2022
Hydrogen energy is an excellent carrier for connecting various renewable energy sources and has many advantages. However, hydrogen is flammable and explosive, and its density is low and easy to escape, which brings inconvenience to the storage and ...
Jianjun Liu, Yong Ma, Jinggang Yang, Lei Sun, Dongliang Guo, Peng Xiao   +5 more
doaj   +1 more source

High energy density carbon–cement supercapacitors for architectural energy storage

Proceedings of the National Academy of Sciences
Electron-conducting carbon concrete (ecˆ3) is a multifunctional cement-based composite material that combines mechanical robustness with electrochemical energy storage. To further expand our understanding of structure–function relationships in this complex multiphase material system and provide a roadmap for transitioning this technology from a simple ...
Damian Stefaniuk, James C. Weaver, Franz-Josef Ulm, Admir Masic   +3 more
openaire   +2 more sources