Results 61 to 70 of about 1,752,642 (285)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Sleep Staging Method Based on Multimodal Physiological Signals Using Snake–ACO

open access: yesApplied Sciences
Non-invasive electrocardiogram (ECG) and respiratory signals are easy to acquire via low-cost sensors, making them promising alternatives for sleep staging. However, existing methods using these signals often yield insufficient accuracy.
Wenjing Chu   +6 more
doaj   +1 more source

The role of thermal energy storage in industrial energy conservation [PDF]

open access: yes, 1979
Thermal Energy Storage for Industrial Applications is a major thrust of the Department of Energy's Thermal Energy Storage Program. Utilizing Thermal Energy Storage (TES) with process or reject heat recovery systems is shown to be extremely beneficial ...
Duscha, R. A., Masica, W. J.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Ground-source heat pumps and underground thermal energy storage: energy for the future [PDF]

open access: yes, 2008
We need energy for space heating—but in most cases not where or when energy sources are available. Energy storage, which helps match energy supply and demand, has been practised for centuries, also in Norway.
Banks, D.   +4 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Multiscale Feature Enhancement and Bidirectional Temporal Dependency Networks for Arrhythmia Classification

open access: yesBiology
Cardiac arrhythmias, especially premature beats and atrial fibrillation, pose substantial clinical risks and detection hurdles. While deep learning has shown promise for automated arrhythmia diagnosis, single-model architectures often lack sufficient ...
Liuwang Yang   +6 more
doaj   +1 more source

A summary of the 1983 Integrated Flywheel Technology Workshop [PDF]

open access: yes, 1984
The use of flywheels to perform the functions of attitude control and/or energy storage on a variety of space missions was studied. Integrated Flywheel Technology was discussed.
Keckler, C. R.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

SPL-YOLOv8: A Lightweight Method for Rape Flower Cluster Detection and Counting Based on YOLOv8n

open access: yesAlgorithms
The flowering stage is a critical phase in the growth of rapeseed crops, and non-destructive, high-throughput quantitative analysis of rape flower clusters in field environments holds significant importance for rapeseed breeding.
Yue Fang   +3 more
doaj   +1 more source

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