Results 81 to 90 of about 468,271 (297)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Lithium-Ion Battery State of Health Estimation Based on Multi-Dimensional Health Characteristics and GAPSO-BiGRU

Energies
The state of health (SOH) of lithium-ion batteries (LIBs) is a key parameter that is crucial for delaying their lifespan degradation and ensuring safe use.
Lv Zhou, Yu Zhang, Kuiting Pan, Xiongfan Cheng   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Exploration of LiCoO2-doped cobalt oxide composite for thermochemical energy storage at high temperature

, 2022
Due to the high energy storage density, long-term energy storage and long-distance transport possibility, as well as operation possibility under open system, metal oxide-based thermochemical energy storage (TCS) was considered as a promising candidate ...
Wu, Rongjun, Mitsuhiro Kubota, Noriyuki Kobayashi, Kubota, Mitsuhiro, Deng, Lisheng, Rongjun Wu, Huang, Hongyu, Lisheng Deng, Hongyu Huang, Kobayashi, Noriyuki   +9 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Fault Diagnosis Method for Lithium-Ion Power Battery Incorporating Multidimensional Fault Features

Energies
Accurately identifying a specific faulty monomer in a battery pack in the early stages of battery failure is essential to preventing safety accidents and minimizing property damage.
Fan Zhang, Xiao Zheng, Zixuan Xing, Minghu Wu   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

EV Dynamic Charging and Discharging Strategy Considering Integrated Energy Station Congestion and Electricity Trading

Energies
As the electrification of transportation systems accelerates, incentivizing electric vehicle (EV) participation in vehicle-to-grid (V2G) operations is becoming increasingly crucial.
Xiang Liao, Haiwei Wang, Yujie Cheng, Dianling Zhan   +3 more
doaj   +1 more source

Hybrid Model Predictive Control Strategy of Supercapacitor Energy Storage System Based on Double Active Bridge

Energies, 2019
In order to solve the problem of which the dynamic response of a supercapacitor (SC) is limited due to the mismatch dynamic characteristics between the DC/DC converter and supercapacitor in an energy storage system, this paper proposes a hybrid model ...
Lujun Wang, Jiong Guo, Chen Xu, Tiezhou Wu, Huipin Lin   +4 more
doaj   +1 more source

Multi-objective optimization of a hybrid energy system integrated with solar-wind-PEMFC and energy storage

, 2023
The move towards achieving carbon neutrality has sparked interest in combining multiple energy sources to promote renewable penetration. This paper presents a proposition for a hybrid energy system that integrates solar, wind, electrolyzer, hydrogen ...
Gui, P., Peipei Gui, Xiaoyu Zhu, Han, Z., Xingxing Zhang, Yu Li, Li, Y., Zhang, Xingxing,, Zhijiang Han, Zhu, X.   +9 more
core   +1 more source