Results 121 to 130 of about 136,814 (309)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Asymmetric Price Responses and the Underlying Energy Demand Trend: Are they Substitutes or Complements? Evidence from Modelling OECD Aggregate Energy Demand [PDF]

A number of energy demand studies have considered the importance of modelling Asymmetric Price Responses (APR), for example, the often-cited work of Gately and Huntington (2002). Griffin and Schulman (2005) questioned the asymmetric approach arguing that
Olutomi I Adeyemi, Guy Judge, David C Broadstock, Lester C Hunt, Mona Chitnis   +4 more
core  

Steps towards sustainable manufacturing through modelling material, energy and waste flows [PDF]

, 2012
A sustainable society cannot be realised without more efficient approaches and technologies, which must in part be provided by manufacturing. Available literature covers the principles for making manufacturing more sustainable, but there is little, if
Ball, Peter, Ball, Peter D., Smith, Leigh   +2 more
core   +1 more source

Supporting energy system modelling in developing countries: Techno-economic energy dataset for open modelling of decarbonization pathways in Colombia. [PDF]

Data Brief, 2023
Plazas-Niño FA, Ortiz-Pimiento NR, Quirós-Tortós J.   +2 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Open energy system modelling to support the European Green Deal. [PDF]

F1000Res, 2022
Süsser D, Pickering B, Hülk L, Pfenninger S.   +3 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

ASEAN’s Energy Transition towards Cleaner Energy System: Energy Modelling Scenarios and Policy Implications

, 2021
The Association of Southeast Asian Nations (ASEAN) faces tremendous challenges regarding the future energy landscape and how the energy transition will embrace a new architecture—including sound policies and technologies to ensure energy access together ...
Han Phoumin, Fukunari Kimura, Jun Arima
core   +1 more source

How Do Dietary Choices Influence the Energy-System Cost of Stabilizing the Climate?

Energies, 2017
We investigate how different global dietary scenarios affect the constraints on, and costs of, transforming the energy system to reach a global temperature stabilization limit of 2 °C above the pre-industrial level.
David Bryngelsson, Fredrik Hedenus, Daniel J. A. Johansson, Christian Azar, Stefan Wirsenius   +4 more
doaj   +1 more source

Selected 'Starter kit' energy system modelling data for selected countries in Africa, East Asia, and South America (#CCG, 2021). [PDF]

Data Brief, 2022
Allington L, Cannone C, Pappis I, Cervantes Barron K, Usher W, Pye S, Brown E, Howells M, Zachau Walker M, Ahsan A, Charbonnier F, Halloran C, Hirmer S, Cronin J, Taliotis C, Sundin C, Sridharan V, Ramos E, Brinkerink M, Deane P, Gritsevskyi A, Moura G, Rouget A, Wogan D, Barcelona E, Niet T, Rogner H, Bock F, Quirós-Tortós J, Angulo-Paniagua J, Krishnamurthy S, Harrison J, To LS.   +32 more
europepmc   +1 more source