Results 81 to 90 of about 11,230,899 (364)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Porphyrin‐Ryleneimide Hybrids: Low‐Bandgap Acceptors in Energy‐Transfer Cassettes [PDF]
, 2020 Ewelina Janiga +5 more
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
南方能源建设[Objective] The hydrogen production system based on solar electrolysis of water is limited by the volatility and intermittency of solar energy, the conversion efficiency of the photovoltaic system, and the performance of the electrolysis cell.
Mengwei MIAO +4 more
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Nano-Micro Letters, 2019 Effective utilization of hot electrons generated from the decay of surface plasmon resonance in metal nanoparticles is conductive to improve solar water splitting efficiency.
Lixia Sang, Lei Lei, Clemens Burda
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Corollary of Energy Transfer On Luminescence From Ce3+ / Eu3+ Co-Activated Glasses For White Light-Emitting Diodes [PDF]
, 2021 openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Erratum to: Semi-Implicit and Semidiscrete Difference Schemes for Solving a Nonstationary Kinetic Equation of Thermal Radiative Transfer and Energy Equation [PDF]
, 2022 N. Ya. Moiseev, V. M. Shmakov
openalex +1 more source