Results 151 to 160 of about 10,533,673 (391)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Decision Process for Identifying Appropriate Devices for Power Transfer between Voltage Levels in Distribution Grids

Energies
During the energy transition, new types of electrical equipment, especially power electronic devices, are proposed to increase the flexibility of electricity distribution grids.
Nassipkul Dyussembekova, Reiner Schütt, Ingmar Leiße, Bente Ralfs   +3 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Spatio-temporal load shifting for truly clean computing

Advances in Applied Energy
Companies operating datacenters are increasingly committed to procuring renewable energy to reduce their carbon footprint, with a growing emphasis on achieving 24/7 Carbon-Free Energy (CFE) matching—eliminating carbon emissions from electricity use on an
Iegor Riepin, Tom Brown, Victor M. Zavala   +2 more
doaj   +1 more source

Zero energy correction method for non-Hermitian Harmonic oscillator with simultaneous transformation of co-ordinate and momentum: Wave function analysis under Iso-spectral condition

, 2016
We present a complete analysis on energy and wave function of Harmonic oscillator with simultaneous non-hermitian transformation of co-ordinate ($(x \rightarrow \frac{(x+ i\lambda p)}{\sqrt{(1+\beta \lambda)}}$ and momentum $(p \rightarrow \frac{(p+ i ...
Mallick, P., Rath, Biswanath
core  

Fun Science Teaching Materials on the Energy Transformation to Promote Students’ Scientific Literacy

, 2019
This study aims to develop fun science teaching material on the energy transformation to promote scientific literacy of junior high school students. The research is a four-D design of Research and Development.
I. D. Pursitasari, E. Suhardi, Tuti Putikah   +2 more
semanticscholar   +1 more source

Comparison of the canonical transformation and energy functional formalisms for ab initio calculations of self-localized polarons [PDF]

, 2022
Yao Luo, Benjamin K. Chang, Marco Bernardi   +2 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source