This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli +2 more
wiley +1 more source
Two-dimensional superlattice nanocatalysts unlock multimodal energy transformation-driven catalytic therapy. [PDF]
Zhang S +7 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Retraction notice to "Analyzing the influence of financial technology and environmental taxation on energy transformation in BRI nations" [Heliyon 10 (2024) e40635]. [PDF]
Zou Y, Ma N.
europepmc +1 more source
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Ending the energy stalemate: A bipartisan strategy to meet America\u27s energy challenges
reportThis report recommends a revenue-neutral package of measures designed to ensure affordable and reliable supplies of energy for the twenty-first century while responding to growing concern about energy security and the risks of global climate change
National Commission on Energy Policy
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Energy Cycles - The Theory of Energy Transformations
This paper explores the cyclical transformations of energy within the universe through a series of thought experiments informed by logic, imagination, and existing knowledge. While the laws of thermodynamics establish that energy cannot be created or destroyed, questions remain regarding the precise forms into which it transforms and the potential ...
openaire +2 more sources
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Inequality across countries in energy intensities: an analysis of the role of energy transformation and final energy consumption [PDF]
This paper analyzes the role of the energy transformation index and of final energy consumption per GDP unit in the disparities in energy intensity across countries.
Emilio Padilla, Juan Antonio Duro
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