Results 91 to 100 of about 84,575,325 (358)
Energy Strategy Reviews, 2020 An energy system transition in the European Union is required to meet the decarbonisation targets determined in the Paris Agreement. To realise this transition, a reduction in greenhouse gas emissions of at least 80% from 1990 levels by 2050 is required.
Pinar Korkmaz +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Recommendations concerning energy information model documentation, public access, and evaluation [PDF]
, 1979 In this study we provide an analysis of the factors underlying Congressional concern regarding model documentation, policies for public access, and evaluation procedures of the Energy Information Administration (EIA) and its predecessor agencies; we also
Wood, D.O. +3 more
core +1 more source
Energies, 2018 This paper investigates and outlines a cost-energy optimised pathway for the UK food manufacturing industry to attain the national Greenhouse Gas (GHG) emission reduction target of 80%, relative to 1990 levels, by 2050.
Baboo Lesh Gowreesunker +2 more
doaj +1 more source
Energy Economics, 2019 Globalization has integrated nations into a world economy. Based on the world input-output database (WIOD), this paper explored the energy use of the world economy under a household-consumption-based MRIO (multi-region input-output) accounting scheme ...
Guo-Qian Chen +4 more
semanticscholar +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
UK domestic air conditioning: a study of occupant use and energy efficiency [PDF]
, 2008 This paper presents the results of a study of air-conditioning usage in homes in the southeast of England. First part of the study consisted surveying 13 dwellings with air-conditioning for a series of 4 week periods during the summer of 2004.
Young, A., Pathan, A., Oreszczyn, T.
core