Results 111 to 120 of about 2,568,352 (314)

Assumptions for the Annual energy outlook.

open access: yes
Description based on: 1990."DOE/EIA-0527."Vols. for 1990- GPO sales statement incorrect in publication.Mode of access: Internet.Auxiliary document to: Annual energy ...
United States. Office of Energy Markets and End Use.
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Impact of hydrogen onboard storage technologies on the performance of hydrogen fuelled vehicles: A techno-economic well-to-wheel assessment

open access: yes, 2007
Hydrogen onboard storage technologies form an important factor in the overall performance of hydrogen fuelled transportation, both energetically and economically.
Faaij, A.P.C.   +4 more
core  

Impacts of Shading and Glazing Combinations on Residential Energy Use in a Hot Dry Climate [PDF]

open access: yes, 2000
A residential building in Tucson, Arizona, was studied to evaluate opportunities for reducing cooling energy use in a hot dry climate. The reduction of solar heat gain was strongly influenced by spectrally selective windows, architectural shading, and ...
Anderson, R.   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Energy End-Use Technologies for the 21st Century. A Report of the World Energy Council

open access: yes, 2004
This report makes clear the opportunities and places technology development firmly centre stage in meeting and overcoming the challenges confronting the energy industry and policy makers.
Schock, R.   +7 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Energy Activities With Energy Ant

open access: yes, 1975
"This little friend has been created by the Federal Energy Administration to tell kids about energy and how to use it wisely" (p. i)
Federal Energy Administration. Office of Communications and Public Affairs.
core  

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