Results 91 to 100 of about 2,869,904 (312)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Use of Biochar-Producing Gasifier Cookstove Improves Energy Use Efficiency and Indoor Air Quality in Rural Households

open access: yesEnergies, 2019
Biomass fuels dominate the household energy mix in sub-Saharan Africa. Much of it is used inefficiently in poorly ventilated kitchens resulting in indoor air pollution and consumption of large amounts of wood fuel.
James K. Gitau   +4 more
doaj   +1 more source

The Rebound Effect: Some Questions Answered [PDF]

open access: yes
Greenhouse gas (and other pollutant) emissions from energy use are now taken to be a problem both internationally and for individual national and regional governments.
Cathy Xin Cui   +3 more
core  

Building Solutions: Opportunities for Coloradans to Save Energy and Money Through Efficient Home Heating [PDF]

open access: yes, 2008
Proposes ways to improve home heating efficiency to reduce energy use and costs, describes the expected economic benefits to the state, and makes policy recommendations for raising efficiency standards and expanding weatherization assistance ...
Aaron Segel, Danny Katz, Travis Madsen
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Optimizing phosphorus management in wheat-based intercropping systems for enhanced productivity, profitability, energy efficiency, and soil health in Indian Inceptisols

open access: yesFrontiers in Sustainable Food Systems
Phosphorus deficiency in Indian Inceptisols limits crop production due to high fixation, low availability and poor fertilizer use efficiency. Even with recommended fertilizer dose, much of the applied P becomes unavailable, make strategies that enhance ...
Shyam Karan   +16 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Sensor-controlled fertigation management for higher yield and quality in greenhouse hydroponic strawberries

open access: yesFrontiers in Plant Science
Controlled environment agriculture (CEA) for strawberry (Fragaria x ananassa) production has experienced a growth in popularity in recent years, particularly in North America.
George Kerrigan Hutchinson   +4 more
doaj   +1 more source

Energy-delay bounds analysis in wireless multi-hop networks with unreliable radio links [PDF]

open access: yes, 2008
Energy efficiency and transmission delay are very important parameters for wireless multi-hop networks. Previous works that study energy efficiency and delay are based on the assumption of reliable links.
Gorce, Jean-Marie   +2 more
core   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

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