Results 81 to 90 of about 684,924 (266)

Unveiling the Productivity Potential of Vertical Farming Through Diverse Crop Cultivation: An Empirical Analysis

open access: yesAgronomy
While vertical farming may offer high productivity per unit land area and has received increasing attention for urban food production, research has primarily focused on leafy greens and herbs.
Vivek Jadhav   +10 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Role of energy efficiency in energy transition: A decomposition analysis of energy use

open access: yesSolar Compass
The use of energy-efficient technologies tends to reduce the overall energy use of a country and foster the energy transition pathways. However, a change in energy can occur either due to a change in activity effect, intensity effect, or structural ...
Pooja Sharma
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Assessment Of Energy Use And Energy Efficiency In Two Portuguese Slaughterhouses

open access: yes, 2014
{"references": ["D.I. Stern, \"The Role of Energy in Economic Growth\". CCEP working paper 3.10. Centre for Climate Economics & Policy. Crawford School of Economics and Government, the Australian National University, Canberra, 2010.", "R.U. Ayres, J.C.J.M. van den Bergh, D. Lindenberger, B.
Feliciano, Manuel   +4 more
openaire   +3 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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