Results 221 to 230 of about 261,434 (308)
Human Rhinovirus A16 Infection of Mast Cells Promotes T2 and Non‐T2 Immune Responses That Are Modulated by the Airway Epithelium
Allergy, EarlyView.Ying Lai, Ryan C. Murphy, Matthew Liu, Maciej W. Czarnecki, Dane Grosvenor, Kimberly A. Dill‐McFarland, Adrian M. Piliponsky, Jason S. Debley, Matthew C. Altman, Teal S. Hallstrand +9 morewiley +1 more sourceProteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival
Brain Pathology, EarlyView.Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito +19 morewiley +1 more sourceASP-COMPLEX: redefining antimicrobial stewardship to improve outcomes in high-risk patients with severe infections. [PDF]
Rev Esp QuimioterPasquau J, Candel FJ, Del Pozo JL, Estella Á, Hidalgo-Tenorio C, Ruiz-Ramos J, González-Del-Catillo J, Chueca N, López-Medrano F, Merino E, Anguita-Santos F, Garcia-Vidal C, Salavert-Lletí M. +12 moreeuropepmc +1 more sourceDifferential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.Jaime Bernaola, José Antonio Cañas, Álvaro Arranz‐Fragua, José Manuel Rodrigo‐Muñoz, Daniel Rodríguez‐González, Antonio Serrano‐Santiago, Gema Guillén‐Sánchez, Alma Martínez Fernández, Marcela Valverde‐Monge, Diana Betancor, Erwin Javier Pinillos‐Robles, Claudia Rodríguez‐Busto, María Jesús Rodríguez‐Nieto, Joaquín Sastre, Victoria del Pozo +14 morewiley +1 more sourceSchedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes
British Journal of Pharmacology, EarlyView.Background and Purpose
α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...Alberto Santiago‐Balmaseda, Marcos M. Villegas‐Rojas, Isaac Pérez‐Segura, Maricela Espino‐Cambrón, Daniel Martinez‐Fong, Luis O. Soto‐Rojas +5 morewiley +1 more sourceEffect of L-Citrulline Supplementation on Endothelial Function and Body Composition in Post-COVID-19 Syndrome: A Randomized Clinical Trial. [PDF]
NutrientsFernanda SM, Arturo OT, Patricia SM, Dulce GI, Yazmín DG, Gamaliel AO, Susana GA, Samantha HL, Getsemani RS, Gabriela CG, Valeria MV. +10 moreeuropepmc +1 more sourcePrevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors
British Journal of Pharmacology, EarlyView.Background and Purpose
Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.Jinrui Lyu, Rajasekar Nagarajan, Dishary Sharmin, Prithu Mondal, Maltesh Kambali, Muxiao Wang, Jinyan Zhou, Makoto Inoue, James M. Cook, Uwe Rudolph +9 morewiley +1 more sourcePractice effects as a dynamic biomarker of early cognitive change in far-from-onset Huntington's disease. [PDF]
Brain CommunFranch-Marti C, Puig-Davi A, Rodriguez-Antiguedad J, Perez-Perez J, Olmedo-Saura G, Ruiz-Barrio I, Bojtos L, Perez-Carasol L, Tort-Merino A, Pagonabarraga J, Kulisevsky J, Martinez-Horta S. +11 moreeuropepmc +1 more sourceWorldwide Impact of Human Development and Inequality on the Prevalence of Asthma, Rhinoconjunctivitis and Eczema. Global Asthma Network's Ecological Study
Clinical &Experimental Allergy, EarlyView.Global Asthma Network Phase I surveyed children, adolescents, and adults worldwide to assess the prevalence of asthma, rhinoconjunctivitis, and eczema. Human Development Index (HDI) and Gini inequality index (GinI) were important explanatory factors for prevalence variability of these conditions, with hotspots in areas with high HDI and high GinI ...Luis García‐Marcos, Chen‐Yuan Chiang, M. Innes Asher, Guy B. Marks, Asma El Sony, Refiloe Masekela, Karen Bissell, Eamon Ellwood, Philippa Ellwood, Neil Pearce, David P. Strachan, A. Elena Martínez‐Torres, Manuel Sánchez‐Solís, Kevin Mortimer, Eva Morales, The Global Asthma Network Phase I Study Group +15 morewiley +1 more source