Results 231 to 240 of about 949,600 (318)
Human Rhinovirus A16 Infection of Mast Cells Promotes T2 and Non‐T2 Immune Responses That Are Modulated by the Airway Epithelium
Allergy, EarlyView.Ying Lai, Ryan C. Murphy, Matthew Liu, Maciej W. Czarnecki, Dane Grosvenor, Kimberly A. Dill‐McFarland, Adrian M. Piliponsky, Jason S. Debley, Matthew C. Altman, Teal S. Hallstrand +9 morewiley +1 more sourcePrevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors
British Journal of Pharmacology, EarlyView.Background and Purpose
Long‐lasting cognitive deficits after surgery in aged individuals, referred to as perioperative neurocognitive disorder (NCD), are a significant public health concern. Such postoperative cognitive deficits are dependent on the presence of microglia in the brain, which, when activated, trigger neuroinflammation.Jinrui Lyu, Rajasekar Nagarajan, Dishary Sharmin, Prithu Mondal, Maltesh Kambali, Muxiao Wang, Jinyan Zhou, Makoto Inoue, James M. Cook, Uwe Rudolph +9 morewiley +1 more sourceDifferential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators
Allergy, EarlyView.Jaime Bernaola, José Antonio Cañas, Álvaro Arranz‐Fragua, José Manuel Rodrigo‐Muñoz, Daniel Rodríguez‐González, Antonio Serrano‐Santiago, Gema Guillén‐Sánchez, Alma Martínez Fernández, Marcela Valverde‐Monge, Diana Betancor, Erwin Javier Pinillos‐Robles, Claudia Rodríguez‐Busto, María Jesús Rodríguez‐Nieto, Joaquín Sastre, Victoria del Pozo +14 morewiley +1 more sourceWDTC1 Haploinsufficiency as a Cause of Neurodevelopmental Phenotypes
Clinical Genetics, EarlyView.In seven individuals heterozygous for loss‐of‐function or conserved missense variants, we demonstrate that loss of WDTC1 function causes a neurodevelopmental syndrome characterized by developmental delay, intellectual disability, and seizures.Elyssa Smith, Victor Faundes, Xiaonan Zhao, Bixia Zheng, Gang Zhang, Xiao Mao, Emily Danko, Jason Laufman, Thomas Besnard, Bertrand Isidor, Benjamin Cogné, Brynjar Örn Jensson, Telma S. Sulem, Patrick Sulem, Jill A. Rosenfeld, Daryl A. Scott +15 morewiley +1 more sourceAn experimental approach to assess the combined effects of multiple stressors on a large vertebrate species
Conservation Biology, EarlyView.Abstract
The design of experiments to investigate the combined effects of multiple stressors requires exposing target organisms to multiple combinations of stressor doses. Concurrent manipulation of stressors is often infeasible with wildlife, but long‐lasting health effects allow individual health to be used as an integrator of prior stressor exposure.Enrico Pirotta, Catriona M. Harris, Lori H. Schwacke, Len Thomas, Jason B. Allen, Aaron A. Barleycorn, Marco Casoli, Jonathan Crossman, Laura Aichinger Dias, Laura Engleby, Erin LaBrecque, Jenny A. Litz, Katherine A. McHugh, Patrick J. O. Miller, Michael J. Moore, Theoni Photopoulou, Brian M. Quigley, Cynthia R. Smith, Brandon L. Southall, Todd R. Speakman, Ryan Takeshita, Christina N. Toms, Randall S. Wells, Eric S. Zolman, Peter L. Tyack +24 morewiley +1 more sourceEmergence of a novel reassorted high pathogenicity avian influenza A(H5N2) virus associated with severe pneumonia in a young adult. [PDF]
Sci RepVázquez-Pérez JA, Becerril-Vargas E, Ramírez-González JE, Solís-Hernández M, Davis CT, Garciadiego-Fossas P, Villanueva-Reza M, Chávez-Morales HH, Mendoza-Ramírez E, Olivares-Flores CD, Vera-Jiménez AC, Rumbo-Nava U, Guadarrama-Pérez C, Recinos-Carrera EG, Zúñiga J, López-Martínez I, Hernández-Rivas L, Barrera-Badillo G, Colin-Soto N, Flores-Cisneros L, Carbajal-Sandoval G, Vidal-Aguirre D, Arellano-Suarez DS, Aparicio-Antonio R, López-Elizalde R, Alcazar-Ramiro CJ, García-López A, Di H, Kirby M, Jang Y, Lezana-Fernández MA, Hernández-Cárdenas CM. +31 moreeuropepmc +1 more sourceCo‐inheritance of ITGA2B and TUBB1 variants in a family reveals distinct genetic contributions to platelet dysfunction
British Journal of Haematology, EarlyView.Perla Bandini, Nina Borràs, Laura Martin‐Fernandez, Nuria Fernández‐Mosteirín, Maria Reyes Aguinaco, Olga Benítez, Natàlia Comes, Lorena Ramírez, Noemí González, Carina Lera, Carme Altisent, Francisco Vidal, Irene Corrales +12 morewiley +1 more source
