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Results 251 to 260 of about 949,600 (318)

A matched case-control study on Escherichia coli factors contributing to sepsis and septic shock in bacteraemic patients. [PDF]

Commun Med (Lond)
Maldonado N +30 more
europepmc +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte +2 more
wiley +1 more source

Imbalanced immune cell network and suboptimal cell activation: signatures associated with disease severity in vaccine-naïve COVID-19 patients. [PDF]

Front Immunol
Ocaña-Guzman R +9 more
europepmc +1 more source

Institutional Trends in Penicillin Allergy: A New Era of Active Penicillin Allergy Delabeling

Clinical &Experimental Allergy, EarlyView.
Anna Brameli +14 more
wiley +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source

Correction: Benchmarking genome assemblers for four bacterial models based on contiguity, correctness, and completeness. [PDF]

Sci Rep
Rojas-Miranda H, Madrigal-Ly V, Molina-Mora JA. +2 more
europepmc +1 more source

Haemophilia, EarlyView.
ABSTRACT Introduction Women with haemophilia can present manifestations and experience undiagnosed symptoms, which negatively affect their health‐related quality of life (HRQoL). Objective To evaluate the HRQoL in obligate carriers of haemophilia (OCH) versus women non‐carriers of haemophilia (WNCH) in a Colombian population.
Fabian A. Manzano‐Di Zeo +9 more
wiley +1 more source

Hodgkin and non‐Hodgkin lymphomas in the post‐antiretroviral therapy era according to HIV virological suppression

HIV Medicine, EarlyView.
Abstract Objectives Lymphomas remain among the most frequent HIV‐associated malignancies, with risk persisting despite effective virological control. This study describes the clinical, epidemiological and prognostic characteristics of lymphomas (both Hodgkin [HL] and non‐Hodgkin [NHL]) in people living with HIV (PLWH), according to virological ...
Teresa Aldámiz‐Echevarria +555 more
wiley +1 more source

High‐Dimensional Immune Profiling Identifies Circulating NKT‐Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset

Immunology, EarlyView.
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro +10 more
wiley +1 more source

[Interdependent islands: health policies and medical practices in the care, management, and research of a neglected disease in the Global South]. [PDF]

Cad Saude Publica
Silveti L, Pereira AMM.
europepmc +1 more source

medicine
medicina
r5-920

medicine general
3. good health