Results 11 to 20 of about 7,578 (209)

Impact of Pre-Heart Transplant Levosimendan Administration on Post-Transplant Vasoplegia and Primary Graft Dysfunction. [PDF]

open access: yesClin Transplant
ABSTRACT Introduction Levosimendan, a calcium‐sensitizing inotropic agent, is used in patients with advanced heart failure (HF) awaiting heart transplantation (HT). Its prolonged effects, due to an active metabolite, may influence post‐transplant vasodilation, particularly when administered shortly before HT.
Guzman-Bofarull J   +9 more
europepmc   +2 more sources

Emerging roles of interferon-stimulated gene-15 in age-related telomere attrition, the DNA damage response, and cardiovascular disease

open access: yesFrontiers in Cell and Developmental Biology, 2023
Population aging and age-related cardiovascular disease (CVD) are becoming increasingly prevalent worldwide, generating a huge medical and socioeconomic burden.
María González-Amor   +5 more
doaj   +1 more source

Sin elevación, también puede haber oclusión

open access: yesRevista Colombiana de Cardiología, 2022
Ante un dolor torácico agudo y evidencia de elevación del segmento ST, se debe instaurar un tratamiento de reperfusión urgente, con el objetivo de abrir la arteria ocluida y minimizar el daño miocárdico y, así, mejorar el pronóstico del paciente.
Mario García-Gómez   +4 more
doaj   +1 more source

Prevención de la cardiotoxicidad en pacientes que reciben quimioterapia

open access: yesRevista Médica Clínica Las Condes, 2012
Antraciclínicos, trastuzumab e inhibidores de tirosin kinasa moléculas pequeñas son agentes antitumorales muy eficaces, pero que producen toxicidad miocárdica, con diferentes intensidades y frecuencias; los mecanismos implicados en la cardiotoxicidad se ...
Florenzano U. Fernando, Dr.   +1 more
doaj   +1 more source

Pulmonary Vascular Remodeling and Prognosis in Patients Evaluated for Heart Transplantation: Insights from the OCTOPUS-CHF Study

open access: yesJournal of Cardiovascular Development and Disease, 2022
Objective: In patients with advanced heart failure, the intravascular optical coherence tomography (OCT) of subsegmental pulmonary artery measurements is correlated with right heart catheterization parameters. Our aim was to study the prognostic value of
Jorge Martínez-Solano   +18 more
doaj   +1 more source

Compound Heterozygous KCNQ1 Mutations Causing Recessive Romano–Ward Syndrome: Functional Characterization by Mutant Co-expression

open access: yesFrontiers in Cardiovascular Medicine, 2021
Next Generation Sequencing has identified many KCNQ1 genetic variants associated with type 1 long QT or Romano-Ward syndrome, most frequently inherited in an autosomal dominant fashion, although recessive forms have been reported.
Antonia González-Garrido   +9 more
doaj   +1 more source

Fístula congénita de seno no coronariano no dilatado a ventrículo derecho

open access: yesCirugía Cardiovascular, 2014
Las fistulas congénitas desde los senos aórticos a las cavidades cardíacas son lesiones infrecuentes, la mayoría provocadas por la rotura de un aneurisma previo. Las fístulas desde senos normales son aún más raras.
Francisco J. Valera   +5 more
doaj   +1 more source

CIBER-CLAP (CIBERCV Cardioprotection Large Animal Platform): A multicenter preclinical network for testing reproducibility in cardiovascular interventions

open access: yesScientific Reports, 2019
Despite many cardioprotective interventions have shown to protect the heart against ischemia/reperfusion injury in the experimental setting, only few of them have succeeded in translating their findings into positive proof-of-concept clinical trials ...
Xavier Rossello   +15 more
doaj   +1 more source

Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade

open access: yeseLife, 2019
Coronaries are essential for myocardial growth and heart function. Notch is crucial for mouse embryonic angiogenesis, but its role in coronary development remains uncertain. We show Jag1, Dll4 and activated Notch1 receptor expression in sinus venosus (SV)
Stanislao Igor Travisano   +9 more
doaj   +1 more source

Factores de riesgo para mortalidad en falla cardiaca aguda. Análisis de árbol de regresión y clasificación

open access: yesRevista Colombiana de Cardiología, 2020
Resumen: Introducción: la estimación temprana del riesgo en falla cardiaca aguda puede ayudar en la toma de decisiones clínicas. Objetivo: identificar los factores de riesgo asociados a mortalidad intrahospitalaria en pacientes con falla cardiaca aguda.
Fernando Fortich   +8 more
doaj   +1 more source

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