Results 41 to 50 of about 324,235 (170)

Enfermedad cardiovascular y obesidad

open access: yesRevista Vive, 2018
Introducción: Las enfermedades cardiovasculares constituyen la principal causa de muerte a nivel mundial y en conjunto con la obesidad, tienen gran impacto en la salud pública. Objetivo. Relacionar las enfermedades cardiovasculares y la obesidad, en pacientes que acuden a la consulta de cardiología Valencia/Venezuela, en el. Materiales y Métodos.
Darío Saturno   +5 more
openaire   +2 more sources

Tailoring the Atrioventricular Interval During Left Bundle Branch Pacing: Playing With Fusion

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Optimization of biventricular pacing for cardiac resynchronization therapy (CRT) with fusion (fusion‐optimized intervals method) has been shown to improve left ventricular remodeling. However, information on programming the atrioventricular (AV) interval during left bundle branch pacing (LBBP) is scarce.
Margarida Pujol‐Lopez   +9 more
wiley   +1 more source

Role of Extracellular Vesicles as Potential Diagnostic and/or Therapeutic Biomarkers in Chronic Cardiovascular Diseases

open access: yesFrontiers in Cell and Developmental Biology, 2022
Cardiovascular diseases (CVDs) are the first cause of death worldwide. In recent years, there has been great interest in the analysis of extracellular vesicles (EVs), including exosomes and microparticles, as potential mediators of biological ...
Jose Luis Martin-Ventura   +7 more
doaj   +1 more source

A Voxel‐Wise T2 Distribution Framework for Lesion Severity Stratification and Treatment‐Response Assessment in Stroke: Insights Into Suberoylanilide Hydroxamic Acid‐Induced Neuroprotection

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 6, Page 2870-2884, December 2026.
ABSTRACT Purpose To evaluate lesion severity distribution in ischaemic brain lesions in spontaneously hypertensive rats (SHR) subjected to 90‐min transient middle cerebral artery occlusion (tMCAO), and to determine whether epigenetically based neuroprotection modifies lesion severity profiles using a voxel‐wise T2 distribution framework.
Andrea Díaz‐Pérez   +3 more
wiley   +1 more source

Aortic disease in Marfan syndrome is caused by overactivation of sGC-PRKG signaling by NO

open access: yesNature Communications, 2021
Aortic aneurysm and dissection, the major problem linked to Marfan syndrome (MFS), lacks effective pharmacological treatment. Here, the authors show that the NO pathway is overactivated in MFS and that inhibition of guanylate cyclase and cGMP-dependent ...
Andrea de la Fuente-Alonso   +20 more
doaj   +1 more source

Enfermedad cardiovascular aterosclerótica y sexualidad

open access: yesRevista Urología Colombiana / Colombian Urology Journal, 2022
ResumenLa enfermedad cardiovascular aterosclerótica es la primera causa de muerte en todo el mundo, y la principal causa de años de vida perdidos por discapacidad (AVADs) en los adultos. Sus factores de riesgo son muy prevalentes en la población, y su ocurrencia se ha asociado con disfunción sexual tanto en hombres como en mujeres, debido a que ...
Sebastián Galvis-Acevedo   +3 more
openaire   +1 more source

Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum

open access: yesClinical Genetics, Volume 110, Issue 5, Page 605-615, November 2026.
Pathogenic PORCN variants are compatible with male survival in both mosaic and non‐mosaic states, expanding the FDH/PONGOS spectrum and improving diagnosis and genetic counseling. ABSTRACT Pathogenic variants in PORCN cause focal dermal hypoplasia (FDH/Goltz syndrome), an X‐linked dominant disorder historically considered lethal in males, with milder ...
Lucía Miranda‐Alcaraz   +23 more
wiley   +1 more source

Futuro del tratamiento farmacológico de las enfermedades cardiovasculares [PDF]

open access: yes, 2009
Futuro del tratamiento farmacológico de las enfermedades ...
Tamargo Menéndez, Juan, Delpón, Eva
core  

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, Volume 293, Issue 21, Page 6444-6466, November 2026.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

De la paliación neonatal al Fontan: el peaje de la cirugía del corazón univentricular. Análisis de resultados de las diferentes técnicas quirúrgicas

open access: yesCirugía Cardiovascular, 2016
Introducción y objetivos: Evaluación de resultados en cirugía univentricular. Pacientes y métodos: Análisis retrospectivo de 42 pacientes intervenidos entre 2013-2015.
Esteban Sarria García   +6 more
doaj   +1 more source

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