Results 141 to 150 of about 61,462,378 (255)
ZNF865 (BLST) a Novel Regulator of DNA Damage and Cell Senescence in Back Pain
ZNF865 (BLST) has previously been classified as part of the “unknome”, but here in the context of back pain, we demonstrate the first functional characterization of ZNF865. We demonstrate that it regulates genomic stability and subsequent senescence, and that downregulation in the intervertebral disc leads to pain behavior in rodent models.
Christian Lewis +12 more
wiley +1 more source
We assessed whether the maternal perinatal gut microbiome and serum SCFA and cord blood SCFA differ between traditional farming and urban dyads. Women following a farming lifestyle had increased microbial diversity, several differentially abundant bacterial species and functional pathways, and increased circulating SCFA. Overall maternal gut microbiome
Erin C. Davis +7 more
wiley +1 more source
Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth +71 more
wiley +1 more source
Hallan los cambios epigenéticos detrás del síndrome de domesticación de los animales
Científicos del Instituto de Ciencias del Mar de Barcelona del CSIC han descrito los cambios que se producen en un grupo de genes en las etapas tempranas de la domesticación y que desembocan en unos rasgos comunes en todos los animales domésticos.
Piferrer, Francesc, Anastasiadi, Dafni
core
Las enfermedades transmitidas por garrapatas que afectan a los animales domésticos son de gran importancia económica debido a las pérdidas que producen, además de ser el mayor obstáculo para una eficiente producción animal en las regiones tropicales y ...
Fernando López Sánchez +4 more
doaj
ABSTRACT Aim This study aims to investigate whether the Fibroblast Growth Factor 23 (FGF23) modulates the electrical activity of sinoatrial (SAN) cells. The canonical function of FGF23 is to regulate body phosphorus and calcium homeostasis by activating the FGF1 receptors (FGFR1)/α‐Klotho complex in the kidney and parathyroid glands.
Giorgia Bertoli +10 more
wiley +1 more source
[Early detection and active intervention in cognitive decline: A healthcare challenge]. [PDF]
Brugos Miranda D, Larumbe Ilundáin R.
europepmc +1 more source

