Results 161 to 170 of about 246,989 (267)
Macrophage‐Fibroblast Crosstalk Shapes Wound Repair Signaling In Vitro
Intercellular communication between macrophages and fibroblasts is critical for wound healing. Macrophages promoted fibroblast scratch closure through contact‐dependent mechanisms independent of connexins. In contrast, fibroblasts regulated macrophage cytokine secretion via connexin‐43–mediated contact signaling that increased IL10 and paracrine ...
Daniela Enriquez‐Ochoa +12 more
wiley +1 more source
Targeted inactivation of TAK1 induces more rapid muscle atrophy in male mice compared to female mice. In addition, loss of TAK1 impairs mechanical overload–induced phosphorylation of p70S6K and rpS6, leading to blunted muscle hypertrophic growth. TAK1 inactivation also promotes lipid accumulation while reducing fatty acid metabolism in skeletal muscle ...
Meiricris Tomaz da Silva +4 more
wiley +1 more source
Las enfermedades transmitidas por garrapatas que afectan a los animales domésticos son de gran importancia económica debido a las pérdidas que producen, además de ser el mayor obstáculo para una eficiente producción animal en las regiones tropicales y ...
Fernando López Sánchez +4 more
doaj
Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman +15 more
wiley +1 more source
Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review
ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle +26 more
wiley +1 more source
Correction: Emergence of a novel reassorted high pathogenicity avian influenza A(H5N2) virus associated with severe pneumonia in a young adult. [PDF]
Vázquez-Pérez JA +31 more
europepmc +1 more source
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson +8 more
wiley +1 more source
[The impact of global change on infectious disease epidemiology]. [PDF]
Pérez Pérez A +2 more
europepmc +1 more source
Aristóteles y las enfermedades de los animales [PDF]
Berríos Etchegaray, Dr. Patricio
core +1 more source

