Results 161 to 170 of about 1,719 (241)

Increased Brown Adipose Tissue Thermogenesis in Phenylketonuria

MedComm, Volume 7, Issue 6, June 2026.
In phenylketonuria (PKU), elevated phenylalanine (Phe) increases hepatic fibroblast growth factor 21 (FGF21) and thyroid hormones, enhancing brown adipose tissue (BAT) thermogenesis in patients. Central FGF21 reproduces this phenotype in rodents via reduced hypothalamic AMP‐activated protein kinase (AMPK) activity in the ventromedial nucleus of the ...
Noemí López‐Rey, Alba Cabaleiro, María P. Pata, Marion Peyrou, Ánxela Estévez‐Salguero, Paola Fernández‐Sanmartín, Donald A. Morgan, Vitor Ferreira, Paula Sánchez‐Pintos, Cintia Folgueira, Carlos Diéguez, Adela Urisarri, Ismael González‐García, Luisa M. Seoane, Kamal Rahmouni, Francesc Villarroya, María L. Couce, Rubén Nogueiras, Miguel López   +18 more
wiley   +1 more source

[Clinical and obstetric characteristics in women with multiple sclerosis during pregnancy]. [PDF]

Rev Med Inst Mex Seguro Soc
Nava-Escobar ER, Mireles-Ramírez MA, Torres-Mendoza BM, Hernández-Preciado MR, Sánchez-Rosales NA, Márquez-Pedroza J.   +5 more
europepmc   +1 more source

Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1170-1181, June 2026.
ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu, Elizabeth K. Harmon, Justin K. Craig, Huili Yao, Kevin P. Battaile, David K. Johnson, Sandhya Subramanian, Wesley C. Van Voorhis, Mario Rivera, Scott Lovell   +9 more
wiley   +1 more source

Antibody Recognition of Highly and Low-Pathogenic A/H5Nx Influenza Viruses in Sera of Mexican Donors. [PDF]

Pathogens
Cordero-Ortiz M, Solís-Hernández M, Cayetano-Mondragón M, Guzmán NC, Valenzuela O, Mata-Haro V, Giménez-Lirola LG, Hernández J.   +7 more
europepmc   +1 more source

Mitochondrial Transplantation as a New Therapeutic Approach Against Cardiac and Renal Consequences in Male Rats With Myocardial Infarction

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Myocardial infarction (MI) is one of the leading causes of death worldwide. MI is associated with cardiac structural and functional alterations. Among these, cardiac fibrosis may be significantly influenced by mitochondrial dysfunction. We sought to evaluate whether the injection of functional mitochondria from healthy muscle could improve
María Cuesta‐Corral, Alejandro Montoro‐Garrido, Ana Romero‐Miranda, Fabián Islas, Bunty Ramchandani, Ricardo Gredilla, Joaquín Fernández‐Irigoyen, Enrique Santamaría, Beatriz Delgado‐Valero, Sara Jiménez‐González, Raquel Rodrigues Díez, María Luisa Nieto, Victoria Cachofeiro, Ernesto Martínez‐Martínez   +13 more
wiley   +1 more source

[Impact of COVID-19 on dyslipidemia in Ecuador]. [PDF]

Aten Primaria
Ferrés Font M, Salas R.
europepmc   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

British Journal of Pharmacology, Volume 183, Issue 12, Page 3321-3339, June 2026.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva, Lidia Puertas‐Umbert, Judith Alonso, Rafael Almendra‐Pegueros, Saray Varona, Mercedes Camacho, Gemma Arderiu, Lluís Asmarats, Marta Alegret, Jose Martinez‐Gonzalez, Cristina Rodriguez   +10 more
wiley   +1 more source

Expert consensus: first multidisciplinary consensus on nuclear cardiology. [PDF]

Arch Cardiol Mex
Vidal M, Gallego C, Roncancio G, Angarita E, Cárdenas R, Dueñas K, García JC, González G, Granados U, Londoño JL, León JDL, López N, Marín V, Martínez É, Murgueitio R, Mejía A, Rodríguez MJ, Silva E, Uribe LG.   +18 more
europepmc   +1 more source

Beyond Temperature: Relative Humidity Systematically Shifts Juvenile Thermal Performance and Projected Population Growth in a Malaria Vector

Ecology Letters, Volume 29, Issue 6, June 2026.
Understanding how ectotherms respond to environmental change requires accounting for multiple interacting climatic factors; yet relative humidity is rarely integrated with temperature in trait‐based performance frameworks. Using laboratory experiments and an analytic population growth model, we show that humidity systematically modifies juvenile life ...
Paul J. Huxley, Joel J. Brown, Brandyce St. Laurent, Britny Johnson, Olivia Y. Cheung, Anna Asamoah, Brandon D. Hollingsworth, Eric R. Bump, Michael C. Wimberly, Mercedes Pascual, Leah R. Johnson, Courtney C. Murdock   +11 more
wiley   +1 more source

[Chronic pain and persistent pain: Conceptual and clinical differences in pain terminology]. [PDF]

Aten Primaria
Vázquez Canales LM, Perelló-Bratescu A, Domínguez-García M, Morral Fernández A.   +3 more
europepmc   +1 more source