Results 51 to 60 of about 205,493 (258)

Enfermedades infecciosas gastrointestinales [PDF]

, 2014
El presente trabajo fue realizado en el Servicio de Internación Pediátrica NºII del Hospital Dr. Humberto Notti, ubicado en Banderas de los Andes 2603, en el departamento de Guaymallén.
Castro, Romina V., Lama, Janet M., Mancilla, Liliana   +2 more
core  

Péptidos antimicrobianos, una alternativa prometedora para el tratamiento de enfermedades infecciosas

Karger Kompass Neumología, 2018
Los microorganismos causantes de enfermedades en humanos evolucionan constantemente, lo que representa un reto en la búsqueda de tratamientos efectivos contra estos patógenos. Aun cuando en la actualidad se cuenta con diversas alternativas farmacológicas,
Kevin Samael Olascoaga-Del Angel, Grecia Sánchez-Evangelista, Israel Carmona-Navarrete, María del Carmen Galicia-Sánchez, Angélica Gómez-Luna, Susan Janneth Islas-Arollo, Jorge Ismael Castañeda-Sánchez   +6 more
semanticscholar   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Rapid Identification of Relevant Microbial Strains by Identifying Multiple Marker Single Nucleotide Polymorphisms via Amplicon Sequencing: Epidemic Monkeypox Virus as a Proof of Concept

Microbiology Spectrum, 2023
Despite the proven value of applying genomic data for epidemiological purposes, commonly used high-throughput sequencing formats are not adapted to the response times required to intervene and finally control outbreaks.
Sergio Buenestado-Serrano, Marta Herranz, Rosalía Palomino-Cabrera, Cristina Rodríguez-Grande, Daniel Peñas-Utrilla, Andrea Molero-Salinas, Cristina Veintimilla, Pilar Catalán, Roberto Alonso, Patricia Muñoz, Laura Pérez-Lago, Darío García de Viedma   +11 more
doaj   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

Advanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih‐Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P. Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E. Jackrel, Mark A. White, Jai S. Rudra   +13 more
wiley   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

Globalización y enfermedades infecciosas [PDF]

, 2003
En un mundo cada vez más interconectado e interdependiente, el brote de una enfermedad infecciosa en un país realmente podría convertirse en una preocupante situación de emergencia sanitaria para el mundo entero.
Alonso, David
core  

Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM) [PDF]

, 2015
Background Trypanosoma cruzi, causative agent of Chagas disease, displays high intraspecific genetic diversity: six genetic lineages or discrete typing units (DTUs) are currently recognized, termed TcI through TcVI.
Bhattacharyya, T., Burleigh, B.A., Costales, J.A., Garcia-Perez, J., Kotton, C.N., Llewellyn, M.S., Messenger, L.A., Zurita-Leal, A.C.   +7 more
core   +2 more sources

Prevalencia de algunas enfermedades infecciosas en bovinos de resguardos indígenas del Cauca, Colombia, 2017

Revista U D C A Actualidad & Divulgación Científica, 2018
The Cauca region in Colombia has indigenous reservations that have presented different problems associated with the armed conflict, which has limited the entities to carry out bovine disease control programs.
D. C. Rivera, J. Rincón, Juan Carlos Echeverry   +2 more
semanticscholar   +1 more source

Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Iron homeostasis in various pathogenic bacteria is regulated by bacterioferritins (Bfr) which function to store Fe3+ and release Fe2+ as needed for metabolic processes. The Bfr structure consists of 18 kDa subunits in which dimer pairs bind a heme molecule and are assembled into a highly symmetrical 24‐meric spherical structure with an ...
Lijun Liu, Elizabeth K. Harmon, Justin K. Craig, Huili Yao, Kevin P. Battaile, David K. Johnson, Sandhya Subramanian, Wesley C. Van Voorhis, Mario Rivera, Scott Lovell   +9 more
wiley   +1 more source