Results 61 to 70 of about 109,673 (267)

Glyoxalase‐1 Inhibition Leads to Ferroptosis Induction in Lung Cancer Cells: A Dual Mechanism of Action of Hydroxamic Acids Derived from Cysteine

ChemMedChem, Volume 21, Issue 1, January 2026.
A set of three cysteine‐derived hydroxamic acids were synthesized and evaluated for human gloxalase‐1 inhibition and ferroptosis induction activities. Among them, compound 2 exhibited a potent inhibitory effect against human glyoxalase‐1 and induced ferroptosis in non‐small cell lung cancer cell lines, increasing reactive oxygen species production and ...
Josué Martínez‐Miranda, Dolores Aguilar‐Cázares, Angélica Flores–Flores, Miguel Ángel Santos‐Contreras, José S. López‐González, Rodrigo Aguayo‐Ortiz, Rogélio Hernández‐Pando, Francisco Hernández‐Luis   +7 more
wiley   +1 more source

“ESTADO ACTUAL DE LOS BLOQUEADORES DE CANALES DE CALCIO “ (REVISIÓN DE LA LITERATURA) [PDF]

, 2013
Desde el siglo pasado nuestra población ha estado en una transición epidemiológica, es decir que las enfermedades que afectaban en el siglo pasado como las infecciones respiratorias agudas y enfermedades diarreicas agudas, se han visto desplazadas por la
Jaimes García, Javier, Piñon Solís, Enrique Omar   +1 more
core  

Beta‐3 Adrenoreceptor Agonist Mirabegron Improves Right Ventricular Function in a Rat Monocrotaline‐Induced Pulmonary Hypertension Model

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Considering the beta‐3 adrenoceptor agonist, mirabegron, may display vasodilator and cardioprotective properties, we investigated the therapeutic potential of mirabegron in monocrotaline‐induced pulmonary hypertension in rats. High‐dose mirabegron improved right ventricular function, and endothelium‐dependent relaxation in isolated rat ...
Pedro Mendes‐Ferreira, Birger Tielemans, Allard Wagenaar, Caroline Bouzin, Rui Adão, Peter Pokreisz, Delphine De Mulder, Adelino Leite‐Moreira, Carmen Brás‐Silva, Jean‐Luc Balligand, Chantal Dessy, Marion Delcroix, Rozenn Quarck, Catharina Belge   +13 more
wiley   +1 more source

Persistence of lung structural and functional alterations at one year post‐COVID‐19 is associated with increased serum PD‐L2 levels and altered CD4/CD8 ratio

Immunity, Inflammation and Disease
Background Persistent respiratory symptoms and lung abnormalities post‐COVID‐19 are public health problems. This study evaluated biomarkers to stratify high‐risk patients to the development or persistence of post‐COVID‐19 interstitial lung disease ...
Ivette Buendia‐Roldan, Karen Martínez‐Espinosa, Maria‐Jose Aguirre, Hiram Aguilar‐Duran, Alexia Palma‐Lopez, Yadira Palacios, Andy Ruiz, Lucero A. Ramón‐Luing, Ranferi Ocaña‐Guzmán, Gloria Pérez‐Rubio, Ramcés Falfán‐Valencia, Moisés Selman, Leslie Chavez‐Galan   +12 more
doaj   +1 more source

The respiratory geriatric severity index (RGSI): A multidimensional prognostic tool integrating geriatric syndromes to predict in-hospital mortality in older adults with respiratory diseases

Archives of Gerontology and Geriatrics Plus
Background and aims: Older adults hospitalized with respiratory diseases face high mortality risk, but existing prognostic models neglect geriatric vulnerability. We aimed to develop and internally validate the Respiratory Geriatric Severity Index (RGSI),
Daniela Josefina Cataneo-Piña, Natalia Sánchez-Garrido, Blanca Patricia Sánchez-Hernández, Lidia Aurora Mondragón-Posadas, Brenda Paola Castillo-Marmolejo, Adriana Bautista-Ruiz, Miguel Ángel Mendoza-Escamilla, Eduardo Ortiz-Reyes, Elizabeth Pacheco-Marín, María Fernanda Santana-Balderas, Stephanie Michelle Ruiz-Ortiz, Ana Karen Herrera-Hernández, Yolanda Nancy Pérez-García, Rocío de los Ángeles Pardo-Mendoza   +13 more
doaj   +1 more source

Effects of particles material atmospheric pollution on acute respiratory disease in under 5 years of age. [PDF]

, 2015
La contaminación atmosférica constituye uno de los principales problemas ambientales de Chile centro sur y sus efectos en la salud se reconocen parcialmente.

core   +1 more source

Abstract Supplement

Pulmonary Medicine, Volume 2026, Issue 1, 2026.
 
Marzia Folegani, Semonti Nandi
wiley   +1 more source

Enfermedad respiratoria exacerbada por aspirina

, 2022
págs.
Quiralte Enríquez, Joaquín, Ávila Castellano, María del Robledo   +1 more
openaire   +1 more source

Whole‐Genome Sequencing in Galicia Reveals Male‐Biased Pre‐Islamic North African Ancestry, Subtle Population Structure, and Microgeographic Patterns of Disease Risk

The FASEB Journal, Volume 39, Issue 24, 31 December 2025.
Whole genome sequencing of Galicians (GALOMICS; 17.2 M variants) reveals a genetic landscape consistent with broader Iberian patterns, characterized by only five clusters. Phylogenetic analyses indicate recent divergence and mild regional inbreeding.
Jacobo Pardo‐Seco, Alba Camino‐Mera, Xabier Bello, Alberto Gómez‐Carballa, Lúa Castelo‐Martínez, Conrado Martínez‐Cadenas, Federico Martinón‐Torres, Antonio Salas   +7 more
wiley   +1 more source

Molecular characterization of human respiratory syncytial virus in Mexico (season 2023–2024) through whole-genome sequencing

Scientific Reports
Human respiratory syncytial virus (hRSV) is a one of major cause of severe acute respiratory infection (SARI) in young children and the elderly. Because genomic surveillance of hRSV is essential to understand viral evolution and the genetic variation ...
Evelyn Rivera-Toledo, Fidencio Mejıa-Nepomuceno, Enrique Mendoza-Ramırez, America Vera-Jimenez, Eduardo Becerril-Vargas, Victor Hugo Ahumada-Topete, Manuel Castillejos-Lopez, Francisco Bernardo Perez-Orozco, Geovanni Benitez, Miguel Ángel Salazar-Lezama, Josue Daniel Cadeza-Aguilar, Emma Garcia-Colin, Claudia Garrido-Galindo, Justino Regalado-Pineda, John P. Collins, Xiang-Jun Lu, J. Kenneth Wickiser, Joel Armando Vazquez-Perez   +17 more
doaj   +1 more source