Results 41 to 50 of about 7,451 (303)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

COSTUME FISCAL E A NORMATIVIDADE DAS PRÁTICAS REITERADAS DA ADMINISTRAÇÃO: UMA LEITURA SISTÊMICA DO DIREITO TRIBUTÁRIO

Revista Direito GV
O sentido de determinados atos normativos é muitas vezes construído no cotidiano, ao longo do tempo, em certo contexto histórico bem localizado, de forma difusa e pulverizada entre os atores sociais, sem uma instância centralizada de decisão que declare ...
Rafael Köche
doaj   +1 more source

Predictive runtime enforcement [PDF]

Proceedings of the 31st Annual ACM Symposium on Applied Computing, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jéron, Thierry, Preoteasa, Viorel, Falcone, Yliès, Tripakis, Stavros, Marchand, Hervé, Pinisetty, Srinivas   +6 more
openaire   +4 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Immediate enforceability of judgments on merits in civil litigation [PDF]

, 2022
Wydział Prawa i AdministracjiRozprawa została podzielona na sześć rozdziałów. Rozdział I charakteryzuje wyrok i nakaz zapłaty na tle innych orzeczeń w procesie cywilnym, definiuje pojęcie wykonalności orzeczenia i omawia wykonalność w aspekcie czasowym ...
Sokólska, Katarzyna
core  

Enforceability of Noncompetition Agreements and Forced Turnovers of Chief Executive Officers

, 2022
We examine whether corporate boards factor the potential cost of competitive harm caused by a departing chief executive officer (CEO) into their forced-turnover decisions.
Seo, Hojun, Lin, Y., Lin, Yupeng, Peters, Florian, Seo, H., Peters, F.S.   +5 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The rigor of immediate enforceability in investment processes in construction sector

Journal of Modern Science, 2019
Objectives The rigor of immediate enforceability in investment processes in construction sector Material and methods The legal dogmatic method. The study of legal acts and case law.
Sebastian Krzysztof Bentkowski
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source