Results 41 to 50 of about 11,176 (289)
Promulguer la loi sous la Révolution : éléments d’histoire critique
Clio@Themis, 2021 To “promulgate law” comes from the Roman language and means “to make law public”. According to Roman law, promulgation is considered a synonym for “publishing” law, and was aimed at making law compulsory.
Jérôme Ferrand
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Revista Latinoamericana de Derechos Humanos, 2018 This paper problematizes around the myths and truths of civil and political rights, and of economic, social, and cultural rights, especially with regard to their legal enforceability. To do this, the article takes a normative approach to how both "groups"
Agustina Pérez
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A Framework for Effective Smart Contracting
Bratislava Law Review, 2023 Smart contracts are event-driven computer programs used to automatically execute all or parts of the agreements between two or more entities, pursuant to their specifications.
Ioana Vasiu, Lucian Vasiu
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‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Definitions of Pasteurization and Their Enforcement [PDF]
Public Health Reports (1896-1970), 1927 TIHERE CAN BE no question that l)asteurization is the most potent single force operating to-day to prevent the transmission of milk-borne disease. In most fields of public health, however, actual practice tends to fall short of the laboratory ideal, and the conviction has recently become more and more acute that -this is true of present-day commercial ...
L C, Frank, F J, Moss, P E, Le Fevre
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Revista Direito GVO sentido de determinados atos normativos é muitas vezes construído no cotidiano, ao longo do tempo, em certo contexto histórico bem localizado, de forma difusa e pulverizada entre os atores sociais, sem uma instância centralizada de decisão que declare ...
Rafael Köche
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On Avoider-Enforcer Games [PDF]
SIAM Journal on Discrete Mathematics, 2009 10 ...
József Balogh, Ryan R. Martin
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