Results 21 to 30 of about 198,844 (286)
Accountability Gaps in the Single Supervisory Mechanism (SSM) Framework
Utrecht Journal of International and European Law, 2018 The first judgement of the General Court (EU) pertaining to the Single Supervision Mechanism (SSM) raised an issue concerning the source of the shared supervisory powers in the system of EU prudential supervision.
Argyro Karagianni, Miroslava Scholten
doaj +1 more source
Is travel actually risky? A study of situational causes of victimization
Crime Science, 2018 Objective We present a first test using a smartphone time use survey app for whether the risk of criminal victimization is higher while traveling than during other activities, and assess risk heterogeneity between public transport, private transport by ...
Stijn Ruiter, Wim Bernasco
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Pharmacovigilance in Israel – tools, processes, and actions
Israel Journal of Health Policy Research, 2017 Background Due to the limited safety data available at the time that a new medication is first marketed, it is essential to continue the collection and monitoring of safety data about adverse drug reactions (ADRs) during the medication’s life cycle. This
Eyal Schwartzberg +4 more
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Spatial Nature and Geographical Characteristics of Drug Crime in Hungary
Laws, 2022 Relatively few people in Hungary deal with the investigation of the spatial nature of crime. In connection with drug crime, we rarely find research dealing with this topic.
Szabolcs Mátyás, Endre Nyitrai
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Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Israel Journal of Health Policy Research, 2017 The correct and rational use of medications can have a positive direct impact on disease outcomes, as well on the utilization of the health system resources.
Eyal Schwartzberg +3 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source