Results 31 to 40 of about 488,003 (314)
1998 Annual Report of the Clean Water Enforcement Act
, 1999 The department is pleased to submit this 1998 Annual report to the Governor and the Legislature in accordance with the requirements of the Clean Water Enforcement Act (CWEA), P.L. 1990, c.28.
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Elections for the Authorities, Elections for Citizens
Управленческое консультирование, 2022 The purpose of this article is to study elections from the perspective of the motivation of society’s participation in them. The interests of professional political subjects and the people are differentiated.A comparative analysis of a number of models ...
N. V. Perevyshin
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Pharmacovigilance in Israel – tools, processes, and actions
Israel Journal of Health Policy Research, 2017 Background Due to the limited safety data available at the time that a new medication is first marketed, it is essential to continue the collection and monitoring of safety data about adverse drug reactions (ADRs) during the medication’s life cycle. This
Eyal Schwartzberg +4 more
doaj +1 more source
Definitions of Pasteurization and Their Enforcement [PDF]
Public Health Reports (1896-1970), 1927 TIHERE CAN BE no question that l)asteurization is the most potent single force operating to-day to prevent the transmission of milk-borne disease. In most fields of public health, however, actual practice tends to fall short of the laboratory ideal, and the conviction has recently become more and more acute that -this is true of present-day commercial ...
L C, Frank, F J, Moss, P E, Le Fevre
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Accountability Gaps in the Single Supervisory Mechanism (SSM) Framework
Utrecht Journal of International and European Law, 2018 The first judgement of the General Court (EU) pertaining to the Single Supervision Mechanism (SSM) raised an issue concerning the source of the shared supervisory powers in the system of EU prudential supervision.
Argyro Karagianni, Miroslava Scholten
doaj +1 more source
On Avoider-Enforcer Games [PDF]
SIAM Journal on Discrete Mathematics, 2009 10 ...
József Balogh, Ryan R. Martin
openaire +2 more sources