Results 31 to 40 of about 123,548 (269)

Enforced death: enforced life. [PDF]

open access: yesJournal of Medical Ethics, 1991
The notion of 'quality of life' frequently features in discussions about how it is appropriate to treat folk at the beginning and at the end of life. It is argued that there is a disjunction between its use in these two areas (1). In the case of disabled babies at the very beginning of life, 'quality of life' considerations are frequently used to ...
openaire   +2 more sources

Predictive runtime enforcement [PDF]

open access: yesProceedings of the 31st Annual ACM Symposium on Applied Computing, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jéron, Thierry   +6 more
openaire   +4 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Strategies for patient empowerment through the promotion of medicines in Israel: regulatory framework for the pharmaceutical industry

open access: yesIsrael Journal of Health Policy Research, 2017
The correct and rational use of medications can have a positive direct impact on disease outcomes, as well on the utilization of the health system resources.
Eyal Schwartzberg   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Crime reporting and victim satisfaction with the police: a large-scale study among victims of crime in the Netherlands

open access: yesCrime Science
Objectives There is a rich body of research on how and why victims report crime to police, but little is known about the crime reporting process itself.
Roselle P. Jansen   +2 more
doaj   +1 more source

GNTI: Gaussian noise-based trajectory imputation via self-supervised learning

open access: yesJournal of Highway and Transportation Research and Development
Trajectory imputation aims to reconstruct complete movement sequences from noisy or incomplete GPS data, crucial for intelligent transportation systems (ITS).
Siqi Liu   +5 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Definitions of Pasteurization and Their Enforcement [PDF]

open access: yesPublic Health Reports (1896-1970), 1927
TIHERE CAN BE no question that l)asteurization is the most potent single force operating to-day to prevent the transmission of milk-borne disease. In most fields of public health, however, actual practice tends to fall short of the laboratory ideal, and the conviction has recently become more and more acute that -this is true of present-day commercial ...
L C, Frank, F J, Moss, P E, Le Fevre
openaire   +2 more sources

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