Results 21 to 30 of about 1,622,488 (349)

Elections for the Authorities, Elections for Citizens

open access: yesУправленческое консультирование, 2022
The purpose of this article is to study elections from the perspective of the motivation of society’s participation in them. The interests of professional political subjects and the people are differentiated.A comparative analysis of a number of models ...
N. V. Perevyshin
doaj   +1 more source

Accountability Gaps in the Single Supervisory Mechanism (SSM) Framework

open access: yesUtrecht Journal of International and European Law, 2018
The first judgement of the General Court (EU) pertaining to the Single Supervision Mechanism (SSM) raised an issue concerning the source of the shared supervisory powers in the system of EU prudential supervision.
Argyro Karagianni, Miroslava Scholten
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Comparative analysis of metals, pesticides, mycotoxins, microbial contaminants and THC potency in illegal and regulated cannabis inflorescences in Canada

open access: yesJournal of Cannabis Research
Background Following the legalization of recreational cannabis in Canada under the Cannabis Act (2018), regulatory frameworks were implemented to ensure product safety, quality, and consistency within the legal market.
Quinton Fiering   +35 more
doaj   +1 more source

Is travel actually risky? A study of situational causes of victimization

open access: yesCrime Science, 2018
Objective We present a first test using a smartphone time use survey app for whether the risk of criminal victimization is higher while traveling than during other activities, and assess risk heterogeneity between public transport, private transport by ...
Stijn Ruiter, Wim Bernasco
doaj   +1 more source

Enforcement of regulation, informal labor and firm performance [PDF]

open access: yes, 2006
This paper investigates how enforcement of labor regulation affects the firm’s use of informal labor and firm performance. Using firm level data on informal employment and firm performance, and administrative data on enforcement of regulation at the ...
Almeida, R., Carneiro, P.
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Pharmacovigilance in Israel – tools, processes, and actions

open access: yesIsrael Journal of Health Policy Research, 2017
Background Due to the limited safety data available at the time that a new medication is first marketed, it is essential to continue the collection and monitoring of safety data about adverse drug reactions (ADRs) during the medication’s life cycle. This
Eyal Schwartzberg   +4 more
doaj   +1 more source

Firms, Courts, and Reputation Mechanisms: Towards a Positive Theory of Private Ordering [PDF]

open access: yes, 2004
This Essay formulates a positive model that predicts when commercial parties will employ private ordering to enforce their agreements. The typical enforcement mechanism associated with private ordering is the reputation mechanism, in which a merchant ...
Richman, Barak D.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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