Results 61 to 70 of about 997,351 (299)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Acknowledgements

Engaged Scholar Journal, 2018
The quality of our Journal depends on scholarly collaboration between the two groups of scholars: the authors, and the anonymous peer-reviewers. We thank both groups for their interest in and support of our Journal.
Engaged Scholar Journal
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A developmental lens for understanding the preparation of culturally responsive school leaders [PDF]

School-University Partnerships
PurposeThe purpose of this article is to examine how pre-service leaders enrolled in a district–university leadership preparation program expressed their understandings of culturally responsive school leadership (CRSL).Design/methodology/approachWe apply
Shanna Dawn Anderson, Donna Volpe, Monika Tiwari, Rachel Garver   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Feasibility and preliminary outcomes of a culturally adapted motivational interviewing intervention to reduce early childhood caries among children of two American Indian communities

Discover Public Health
Objective Early childhood caries (ECC) are prevalent among ethnic minoritized children in the US. Specifically, American Indian/Alaska Native (AI/AN) children face the highest burden of ECC compared to other children. Oral health (OH) interventions using
Julie A. Baldwin, Steven D. Barger, Christine Kirby, Skyler J. Bordeaux, Sara Young, Gerlinda Morrison, Stephanie Hyeoma, Kristan Elwell, Marissa Tutt, Carolyn Camplain, Heather Thomas, Chloe Horowitz, Rachel Whitman, Kathryn Bezue   +13 more
doaj   +1 more source

Beyond Employability: Defamiliarizing Work-Integrated Learning with Community-Engaged Learning

, 2019
Within the context of an increasing interest in forms of work-integrated learning (WIL) among governments and institutions of higher education, this essay explores the relation between WIL and community-engaged learning (CEL) in order to argue that the ...
Esmail, Jennifer, Brabazon, Honor, Stirling, Ashley, Locklin, Reid   +3 more
core   +1 more source

Boundary spanning leadership among community-engaged faculty: An exploratory study of faculty participating in higher education community engagement

, 2020
The purpose of this study was to explore faculty members’ perceptions of their roles as boundary spanners, the expectations they have for professional competencies related to boundary spanning, and how these faculty were prepared to successfully perform ...
Purcell, Jennifer W., Pearl, Andrew, Van Schyndel, Trina   +2 more
core   +1 more source