Results 81 to 90 of about 1,219,757 (285)

Reconnecting through Urban Agriculture: A community-engaged video ethnography in Winnipeg [PDF]

, 2020
: While contemporary urban life in many ways seems increasingly disconnected from nature, the growing practice of urban agriculture – growing food in and around cities – is increasingly pointed to as a source of well-being through a connection to the ...
Baird, Natalie, Hallberg, Avery, Bowness, Evan, Packulak, Mark   +3 more
core   +1 more source

Using action research and a community-academic partnership to understand clinical trial participation: a patient-centered perspective

Research Involvement and Engagement
Background Clinical trials that are patient-centered appear to be more successful (e.g., clinical outcomes, improved communication, mutual empowerment, changed attitudes), thus, action research may be a field of importance. The current study explores the
Sara Santarossa, Michele Baber, Janine Hussein, Chrystal Oley, Kristen Slangerup, Dana Murphy, Karen E. Kippen   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Replanting Cultures: Community-Engaged Scholarship in Indian Country by Chief Benjamin J. Barnes, Stephen Warren (eds). United Kingdom: State University of New York Press, 2022. 376pp. ISBN 9781438489957.

, 2023
Kelly, Mckelvey, Mckelvey Kelly
core   +1 more source

Working together: a methodological case study of 'engaged scholarship'

, 2010
The concept of engaged scholarship, as a 'new' and participatory approach to knowledge production, has received much attention over the past decade. However, the term is clouded in ambiguity.
Cuthill, Michael
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Community Resource Handbook 2021: A Guide to Community Engaged Research

, 2021
About CERi: Based out of the 312 Main co-working space in downtown Vancouver, CERi is focused on extending community-engaged research to provincial, national and international communities.
Fraser, Patti, Wong, Jackie, Grain, Kari, Mahoney, Tara   +3 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Translating positionality into practice: a case study on capacity building for community-based dissemination among early-stage investigators

Frontiers in Communication
The Fairness First Campaign (FFC) was developed within the Southwest Health Engagement and Research Collaborative (SHERC) at Northern Arizona University (NAU) to disseminate stories of health research and community partnerships from researchers, students,
Alexandra Olin, Caroline Mende, Alexandra E. Sammaron Longorio, Carmenlita Chief, Mark Remiker, Regina Eddie, Regina Eddie, Nicolette I. Teufel-Shone, Nicolette I. Teufel-Shone, Samantha Sabo, Samantha Sabo   +10 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source